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Acute Inhibition of Drp1 Mitigates Adverse Cardiac Remodelling following Chronic Reperfused Myocardial Infarction.

作者信息

Donner Daniel G, Kong Anne M, Lees Jarmon G, Kiriazis Helen, Brown Aascha, Tham Yow K, Holien Jessica K, Shen Hsin-Hui, Hausenloy Derek J, Lim Shiang Y

机构信息

Baker Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia.

Central Clinical School, Monash University, Melbourne, Victoria, 3004, Australia.

出版信息

Cardiovasc Drugs Ther. 2024 Oct 21. doi: 10.1007/s10557-024-07633-6.

DOI:10.1007/s10557-024-07633-6
PMID:39432235
Abstract
摘要

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本文引用的文献

1
Mitochondrial Kinase Signaling for Cardioprotection.用于心脏保护的线粒体激酶信号传导
Int J Mol Sci. 2024 Apr 19;25(8):4491. doi: 10.3390/ijms25084491.
2
Targeting mitochondrial shape: at the heart of cardioprotection.靶向线粒体形态：心脏保护的核心。
Basic Res Cardiol. 2023 Nov 13;118(1):49. doi: 10.1007/s00395-023-01019-9.
3
Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer.线粒体功能障碍：心血管疾病与癌症的交汇点
J Transl Med. 2023 Sep 19;21(1):635. doi: 10.1186/s12967-023-04498-5.
4
Mitochondrial Fission as a Therapeutic Target for Metabolic Diseases: Insights into Antioxidant Strategies.线粒体裂变作为代谢性疾病的治疗靶点：对抗氧化策略的见解
Antioxidants (Basel). 2023 May 27;12(6):1163. doi: 10.3390/antiox12061163.
5
A novel small molecule inhibitor of human Drp1.一种新型人源 Drp1 小分子抑制剂。
Sci Rep. 2022 Dec 13;12(1):21531. doi: 10.1038/s41598-022-25464-z.
6
Chronic Pharmacological Modulation of Mitochondrial Dynamics Alleviates Prediabetes-Induced Myocardial Ischemia-Reperfusion Injury by Preventing Mitochondrial Dysfunction and Programmed Apoptosis.线粒体动力学的慢性药理调节通过预防线粒体功能障碍和程序性凋亡减轻前驱糖尿病诱导的心肌缺血再灌注损伤。
Cardiovasc Drugs Ther. 2023 Feb;37(1):89-105. doi: 10.1007/s10557-021-07250-7. Epub 2021 Sep 13.
7
New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology.动力相关蛋白1（Drp1）亚型在调节线粒体病理生理学中作用的新观点。
Pharmacol Ther. 2020 Sep;213:107594. doi: 10.1016/j.pharmthera.2020.107594. Epub 2020 May 29.
8
Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study.靶向线粒体分裂在急性心肌梗死的临床相关大动物模型中使用 Mdivi-1：一项初步研究。
Int J Mol Sci. 2019 Aug 15;20(16):3972. doi: 10.3390/ijms20163972.
9
Inhibition of dynamin-related protein 1 protects against myocardial ischemia-reperfusion injury in diabetic mice.抑制动力相关蛋白1可保护糖尿病小鼠免受心肌缺血再灌注损伤。
Cardiovasc Diabetol. 2017 Feb 7;16(1):19. doi: 10.1186/s12933-017-0501-2.
10
Mitochondrial fission - a drug target for cytoprotection or cytodestruction?线粒体裂变：细胞保护还是细胞破坏的药物靶点？
Pharmacol Res Perspect. 2016 Apr 21;4(3):e00235. doi: 10.1002/prp2.235. eCollection 2016 Jun.