Souro Sanou National Teaching Hospital, Bobo Dioulasso, Burkina Faso.
High Institute of Health Sciences, Nazi Boni University, Bobo Dioulasso, Burkina Faso.
BMC Public Health. 2024 Oct 21;24(1):2900. doi: 10.1186/s12889-024-20389-w.
Human papilloma virus testing is a new method of screening for precancerous cervical lesions. Here we identified factors associated to the positive Human papilloma virus-testing in the context of cervical precancer screening at the Souro Sanou National Teaching Hospital in Burkina Faso.
Conducted from June 2021-May 2022, this was a cross-sectional study, including patients aged between 25 and 55 years-old and screened for precancerous lesions and received HPV-testing at the Department of Gynecology, Obstetrics and Reproductive Medicine (DGORM) of the SSNTH. The proportion of positive HPV-test was calculated, and we identified factors associated to positive HPV-test using logistic regression.
Of the 759 patients came for precancerous lesions screening, 559 patients were included. Their mean-age was 38.8 ± 7.9 years-old, 94.3% were from urban area and 50.3% identified as housewives. Regarding the past medical history, it noted: number of gestures (3.2 ± 2.0), parity (2.8 ± 1.9), number of living children (2.8 ± 1.9), having abortion experience (24.0%), age of first-sexual-intercourse(18.6 ± 2.3 years), alcohol (9.1%) and tobacco (1.0%) consumption, sexually-transmitted-infection (27.0%), Human immunodeficiency virus (HIV)infection (5.0%); none had been vaccinated against HPV. Biologically, 16.6% [95% CI: 13.6-20] of the women had a positive HPV-test. The factors significantly associated with positive HPV-test were: occupation in the private sector [OR: 0.06(0.0-0.5); p < 0.001], having a sexually-transmitted-infection [OR: 3.9(2.0-7.7); p < 0.001], age of first-sexual-intercourse [OR: 0.7(0.6-0.9); p < 0.001], sexual-multiple-partnership [OR: 17.5(8.1-39.6); p < 0.001], and HIV status [OR: 13.2(4.4-40.5); p < 0.001].
These results call for health actions through the reinforcement for behavioral change mainly about sexually-transmitted-infections, and for the raising awareness of the population for the screening related to the precancerous lesions and HIV.
引言：人乳头瘤病毒检测是筛查癌前宫颈病变的新方法。本研究旨在探讨布基纳法索苏罗·萨诺国立教学医院在宫颈癌前筛查背景下人乳头瘤病毒检测阳性的相关因素。
材料与方法：本研究为 2021 年 6 月至 2022 年 5 月进行的一项横断面研究，纳入年龄在 25-55 岁之间、接受癌前病变筛查并在 SSNTH 妇产科和生殖医学系（DGORM）接受 HPV 检测的患者。计算 HPV 检测阳性的比例，并使用逻辑回归识别与 HPV 检测阳性相关的因素。
结果：在 759 名前来筛查癌前病变的患者中，559 名患者被纳入研究。她们的平均年龄为 38.8±7.9 岁，94.3%来自城市地区，50.3%为家庭主妇。在过去的病史方面，记录到：性伴侣数量（3.2±2.0）、产次（2.8±1.9）、活产子女数（2.8±1.9）、流产史（24.0%）、首次性行为年龄（18.6±2.3 岁）、饮酒（9.1%）和吸烟（1.0%）、性传播感染（27.0%）、人类免疫缺陷病毒（HIV）感染（5.0%）；无人接种 HPV 疫苗。生物学上，16.6%[95%CI：13.6-20]的女性 HPV 检测阳性。与 HPV 检测阳性显著相关的因素包括：在私营部门工作[OR：0.06（0.0-0.5）；p<0.001]、性传播感染[OR：3.9（2.0-7.7）；p<0.001]、首次性行为年龄[OR：0.7（0.6-0.9）；p<0.001]、性伴侣数量[OR：17.5（8.1-39.6）；p<0.001]和 HIV 状态[OR：13.2（4.4-40.5）；p<0.001]。
结论：这些结果呼吁通过加强行为改变来采取卫生行动，主要针对性传播感染，并提高人群对癌前病变筛查和 HIV 的认识。
