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危重症患者静脉治疗中医疗与用药一体化管理模式分析

Analysis of the Integrated Management Model of Medical Care and Medication in Intravenous Treatment for Critically Ill Patients.

作者信息

Gao Peng, Wu Yanshuo, Wu Xinhui, Bai Jing, Shen Kangkang, Yin Yanling

机构信息

Department of Critical Care Medicine, Fourth Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.

Department of Pharmacy, Fourth Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.

出版信息

J Multidiscip Healthc. 2024 Oct 17;17:4793-4801. doi: 10.2147/JMDH.S478218. eCollection 2024.

DOI:10.2147/JMDH.S478218
PMID:39434827
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11492917/
Abstract

OBJECTIVE

To explore the effect of the Integrated Management Model of Doctor-Nurse-Pharmacist Collaboration on the Safety of Intravenous Therapy in Critically Ill Patients.

METHODS

1587 patients who were hospitalized in the Intensive Care Department of the Fourth Hospital of Hebei Medical University in China from January 2021 to December 2022 were selected. 768 patients before the implementation of the integrated medical, nursing, and drug management model were selected as the control group, and 819 patients who implemented the integrated medical, nursing, and drug management model were selected as the observation group.

RESULTS

Compared with the control group, the incidence of drug compatibility contraindications in the observation group decreased from 3.5% to 1.5% (χ=6.957 =0.008), the central venous catheter (CVC) blockage rate decreased from 2.5% to 1.0% (χ=5.249 =0.022), the daily incidence of catheter related bloodstream infections decreased from (1.84 ± 2.17) to (0.91 ± 1.19)(t=6.988 =0.015), and the incidence of peripheral venous treatment related complications decreased from 10.3% to 2.9% (χ=16.663 =0.000). Among them, the incidence of phlebitis decreased from 5% to 1.6% (χ=4.817 =0.028). The incidence of drug exudation decreased from 3.4% to 0.8% (χ2=0.031 =0.019). The incidence of extravasation has decreased from 2.5% to 0.4% (χ=0.044 =0.027). The differences were statistically significant (<0.05).

CONCLUSION

The Integrated Management Model of Doctor-Nurse-Pharmacist Collaboration significantly reduced the incidence of catheter-related bloodstream infections (CRBSI), drug incompatibility, and other intravenous therapy-related complications, thereby enhancing the safety of intravenous therapy in critically ill patients.

摘要

目的

探讨医护药协同整合管理模式对重症患者静脉治疗安全性的影响。

方法

选取2021年1月至2022年12月在中国河北医科大学第四医院重症监护科住院的1587例患者。选取实施医护药一体化管理模式前的768例患者作为对照组,选取实施医护药一体化管理模式的819例患者作为观察组。

结果

与对照组相比,观察组药物配伍禁忌发生率由3.5%降至1.5%(χ²=6.957,P =0.008),中心静脉导管(CVC)堵塞率由2.5%降至1.0%(χ²=5.249,P =0.022),导管相关血流感染日发生率由(1.84±2.17)降至(0.91±1.19)(t =6.988,P =0.015),外周静脉治疗相关并发症发生率由10.3%降至2.9%(χ²=16.663,P =0.000)。其中,静脉炎发生率由5%降至1.6%(χ²=4.817,P =0.028)。药物渗出发生率由3.4%降至0.8%(χ²=0.031,P =0.019)。外渗发生率由2.5%降至0.4%(χ²=0.044,P =0.027)。差异具有统计学意义(P<0.05)。

结论

医护药协同整合管理模式显著降低了导管相关血流感染(CRBSI)、药物配伍禁忌及其他静脉治疗相关并发症的发生率,从而提高了重症患者静脉治疗的安全性。

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本文引用的文献

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Complication Rates of Central Venous Catheters: A Systematic Review and Meta-Analysis.中心静脉导管相关并发症发生率:系统评价和荟萃分析。
JAMA Intern Med. 2024 May 1;184(5):474-482. doi: 10.1001/jamainternmed.2023.8232.
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Safety and Efficacy of Midline vs Peripherally Inserted Central Catheters Among Adults Receiving IV Therapy: A Randomized Clinical Trial.成人接受静脉治疗时中线与外周置入中心导管的安全性和有效性:一项随机临床试验。
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Infusion Therapy Standards of Practice, 9th Edition.《输液治疗实践标准》第9版
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Physicochemical Characteristics of Antimicrobials and Practical Recommendations for Intravenous Administration: A Systematic Review.抗菌药物的物理化学特性及静脉给药实用建议:一项系统评价
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