Lopes Camila Soares, Ferrari Esteves Torres Fernanda, Faria Gisele, Sasso-Cerri Estela, Guerreiro-Tanomaru Juliane Maria, Tanomaru-Filho Mario, Cerri Paulo Sérgio
Department of Restorative Dentistry, Dental School, São Paulo State University (Unesp), Araraquara, SP, Brazil.
Department of Morphology, Genetics, Laboratory of Histology and Embryology, Orthodontics and Pediatric Dentistry, Dental School, São Paulo State University (Unesp), Araraquara, SP, Brazil.
Eur Endod J. 2024 Dec 20;9(4):374-382. doi: 10.14744/eej.2024.35219. Epub 2024 Oct 22.
Our purpose was to investigate the physicochemical properties of Bio-C Temp, a bioceramic intracanal medication, and whether its residues remain adhered to the dentine walls after conventional manual irrigation (CMI) or passive ultrasonic irrigation (PUI) in comparison to Calen.
The pH after 12 hours, 1 day, 3 days, 7 days, 14 days, 21 days and 28 days, and the flow, radiopacity, and the solubility of the medications after immersion for 7 and 30 days in distilled water (dH2O) or phosphate-buffered saline (PBS) solution were evaluated. Filling capacity, and volumetric changes after 14 days were assessed by micro-computed tomography (micro-CT). The residues of medications after CMI or PUI were analysed with scanning electron microscopy. Statistical analysis was performed using ANOVA and Tukey's post-hoc test, Student's t test or the Kruskal-Wallis and Dunn post-hoc test (α = 0.05).
Bio-C Temp presented a lower pH, flow, volumetric change, and weight loss after immersion in PBS on the 7th and 14th days (p < 0.05) and greater radiopacity and filling capacity (p < 0.05) than Calen. Both medications showed lower solubility in PBS than in dH2O (p < 0.05). There was no difference in the residue content of the two medications between two irrigation methods in three-thirds of the roots (p > 0.05).
Although Bio-C Temp had less volumetric loss and satisfactory filling capacity, this medication provided lower alkalinity than did Calen. Furthermore, neither CMI nor PUI completely removed the medicament residues within the human root canal.
我们的目的是研究生物陶瓷根管内用药Bio-C Temp的理化性质，以及与Calen相比，在传统手动冲洗（CMI）或被动超声冲洗（PUI）后，其残留物是否仍附着在牙本质壁上。
评估12小时、1天、3天、7天、14天、21天和28天后的pH值，以及药物在蒸馏水（dH2O）或磷酸盐缓冲盐水（PBS）溶液中浸泡7天和30天后的流动性、射线不透性和溶解性。通过微计算机断层扫描（micro-CT）评估14天后的填充能力和体积变化。用扫描电子显微镜分析CMI或PUI后药物的残留物。使用方差分析和Tukey事后检验、学生t检验或Kruskal-Wallis和Dunn事后检验进行统计分析（α = 0.05）。
与Calen相比，Bio-C Temp在第7天和第14天浸泡在PBS中后，pH值、流动性、体积变化和重量损失较低（p < 0.05），射线不透性和填充能力较高（p < 0.05）。两种药物在PBS中的溶解度均低于在dH2O中的溶解度（p < 0.05）。在三分之二的牙根中，两种冲洗方法下两种药物的残留量没有差异（p > 0.05）。
尽管Bio-C Temp的体积损失较小且填充能力令人满意，但该药物的碱性低于Calen。此外，CMI和PUI均未完全清除人根管内的药物残留。
