Tumor Center, Henan Provincial Key Medicine Laboratory of Nursing, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, 450003, China.
Future Oncol. 2024;20(37):3009-3018. doi: 10.1080/14796694.2024.2407757. Epub 2024 Oct 22.
The clinical efficacy of systemic chemotherapy is limited due to the nonspecific delivery of anticancer drugs and is associated with serious systemic adverse effects. Therefore, integrated treatment and comprehensive care are particularly important for postoperative chemotherapy patients with lung cancer. This study aimed to ascertain the application effect of multidisciplinary team (MDT)-style continuity of care combined with whole-process nutritional nursing in postoperative chemotherapy patients with lung cancer. Nutritional indices, immune function, adverse emotions, self-efficacy, self-care ability, quality of life and toxic reactions during chemotherapy were recorded in postoperative chemotherapy patients with lung cancer receiving routine care (control group) and MDT-style continuity of care combined with whole-process nutritional care (intervention group). After care, the intervention group performed higher BMI, PA, TP and ALB, CD3, CD4 and CD4/CD8, lower levels of CD8, lower self-rating anxiety scale, self-rating depression scale and QLQ-C30 symptom domain scores and higher general self-efficacy scale, exercise of self-care agency scale and QLQ-C30 functional domain scores versus the control group (all < 0.05). MDT-style continuity of care combined with whole-process nutritional care can improve the nutritional status of postoperative chemotherapy patients with lung cancer, and in turn enhance their quality of life.
由于抗癌药物的非特异性递送，全身化疗的临床疗效有限，并且与严重的全身不良反应相关。因此，对于肺癌术后化疗患者，综合治疗和全面护理尤为重要。本研究旨在确定多学科团队（MDT）式连续性护理联合全程营养护理在肺癌术后化疗患者中的应用效果。记录接受常规护理（对照组）和 MDT 式连续性护理联合全程营养护理（干预组）的肺癌术后化疗患者的营养指标、免疫功能、不良情绪、自我效能、自我护理能力、生活质量和化疗期间的毒性反应。护理后，干预组的 BMI、PA、TP 和 ALB、CD3、CD4 和 CD4/CD8 更高，CD8 更低，自评焦虑量表、自评抑郁量表和 QLQ-C30 症状领域评分更低，一般自我效能感量表、自我护理能力量表和 QLQ-C30 功能领域评分更高，均优于对照组（均<0.05）。MDT 式连续性护理联合全程营养护理可以改善肺癌术后化疗患者的营养状况，进而提高其生活质量。
