Cantor P, Andersen B N, Rehfeld J F
FEBS Lett. 1986 Jan 20;195(1-2):272-4. doi: 10.1016/0014-5793(86)80175-2.
We have found gastrin in both the adult and neonatal cat pancreas. In contrast with the main production sites, antrum and duodenum, gastrin in the pancreas occurs in a single molecular form, tyrosine O-sulfated gastrin-17. Since tyrosine sulfation increases the pancreozymic effect of gastrin, the complete sulfation seems functionally expedient.
我们在成年和新生猫的胰腺中均发现了胃泌素。与主要产生部位胃窦和十二指肠不同，胰腺中的胃泌素以单一分子形式存在，即酪氨酸O-硫酸化胃泌素-17。由于酪氨酸硫酸化增强了胃泌素的促胰酶作用，这种完全硫酸化在功能上似乎是有利的。
