Jan Muhammad Y, Patidar Kavish R, Ghabril Marwan S, Kubal Chandrashekhar A
Division of Transplant Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.
Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine and Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX.
Transplantation. 2025 Jun 1;109(6):938-944. doi: 10.1097/TP.0000000000005252. Epub 2024 Oct 23.
Postoperative acute kidney injury after liver transplant (LT) has long-term implications for kidney health. LT recipients are at risk of acute kidney injury due to a number of factors related to the donor liver, intraoperative factors including surgical technique, as well as recipient factors, such as pre-LT kidney function and postoperative complications. This review discusses these factors in detail and their impact on posttransplant kidney function. Long-term risk factors such as calcineurin inhibitors have also been discussed. Additionally, the impact of liver allocation policies on pre- and post-LT kidney health is discussed.
肝移植（LT）术后急性肾损伤对肾脏健康具有长期影响。由于与供体肝脏相关的多种因素、包括手术技术在内的术中因素以及受体因素（如LT前肾功能和术后并发症），LT受者有发生急性肾损伤的风险。本综述详细讨论了这些因素及其对移植后肾功能的影响。还讨论了诸如钙调神经磷酸酶抑制剂等长期危险因素。此外，还讨论了肝脏分配政策对LT前后肾脏健康的影响。
