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既往未诊断的晚期人类免疫缺陷病毒(HIV)/获得性免疫缺陷综合征(AIDS)患者中的肺孢子菌肺炎及HIV筛查的重要性

Pneumocystis Pneumonia in Previously Undiagnosed Advanced HIV/AIDS and Importance of HIV Screening.

作者信息

Boggala Mounica, Junaid Muhammad, Zhang Elizabeth

机构信息

Medical School, Lincoln Memorial University - DeBusk College of Osteopathic Medicine, Knoxville, USA.

Internal Medicine, Methodist Le Bonheur Healthcare, Memphis, USA.

出版信息

Cureus. 2024 Sep 22;16(9):e69902. doi: 10.7759/cureus.69902. eCollection 2024 Sep.

Abstract

The diagnosis of human immunodeficiency virus (HIV) in its late stages, also known as acquired immunodeficiency syndrome (AIDS), leads to increased morbidity and mortality. This is mostly due to the time given for opportunistic infections to arise, which present with their own complications. In this case report, we present an otherwise healthy 38-year-old male, who presented with general systemic symptoms and was later found to have HIV and AIDS, ultimately resulting in his death during this hospital admission. This case report will discuss HIV-associated opportunistic infections, focusing more on pneumonia (PCP), and the following complications that arose during the course of this patient's hospitalization. The overarching goal of this case report is to highlight the importance of routine HIV screening in the United States in efforts to decrease mortality from AIDS-related opportunistic infections. In addition to mandating in-hospital screening, educating the public on lifestyle behaviors that can put one at risk for developing HIV is crucial to decreasing the prevalence of cases that go undiagnosed, as well as the disease itself.

摘要

人类免疫缺陷病毒(HIV)晚期诊断,即获得性免疫缺陷综合征(AIDS),会导致发病率和死亡率上升。这主要是因为有时间让机会性感染出现,而这些感染会伴有自身的并发症。在本病例报告中,我们介绍一名38岁原本健康的男性,他出现全身症状,后来被发现感染HIV并患有AIDS,最终在此次住院期间死亡。本病例报告将讨论与HIV相关的机会性感染,重点更多地放在肺炎(肺孢子菌肺炎)以及该患者住院期间出现的以下并发症上。本病例报告的总体目标是强调在美国进行常规HIV筛查对于降低因艾滋病相关机会性感染导致的死亡率的重要性。除了强制进行院内筛查外,教育公众了解可能使其面临感染HIV风险的生活方式行为对于降低未确诊病例的患病率以及疾病本身的患病率至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5f1/11494859/a921e468a894/cureus-0016-00000069902-i01.jpg

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