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High Levels of Vitamin C Intake Modify Effects of Phthalates on Metabolic Dysfunction-associated Steatotic Liver Disease: A Nationally Representative Study.

作者信息

Zhou Ruoqi, Wang Yuwei, Liu Xinxin, Yu Xia, Xia Dajing, Wu Yihua, Shi Yu

机构信息

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

出版信息

J Clin Transl Hepatol. 2024 Oct 28;12(10):892-895. doi: 10.14218/JCTH.2024.00186. Epub 2024 Sep 29.

DOI:10.14218/JCTH.2024.00186
PMID:39440222
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11491502/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b457/11491502/35fd9855a507/JCTH-12-892-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b457/11491502/35fd9855a507/JCTH-12-892-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b457/11491502/35fd9855a507/JCTH-12-892-g001.jpg

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本文引用的文献

1
A multisociety Delphi consensus statement on new fatty liver disease nomenclature.多学会专家组关于新的脂肪肝疾病命名的德尔菲共识声明。
J Hepatol. 2023 Dec;79(6):1542-1556. doi: 10.1016/j.jhep.2023.06.003. Epub 2023 Jun 24.
2
Serum vitamin C levels and risk of non-alcoholic fatty liver disease: results from a cross-sectional study and Mendelian randomization analysis.血清维生素C水平与非酒精性脂肪性肝病风险：一项横断面研究和孟德尔随机化分析的结果
Front Nutr. 2023 May 12;10:1162031. doi: 10.3389/fnut.2023.1162031. eCollection 2023.
3
Changing epidemiology, global trends and implications for outcomes of NAFLD.
非酒精性脂肪性肝病的流行病学变化、全球趋势及其对结局的影响。
J Hepatol. 2023 Sep;79(3):842-852. doi: 10.1016/j.jhep.2023.04.036. Epub 2023 May 9.
4
Vitamin C Deficiency Inhibits Nonalcoholic Fatty Liver Disease Progression through Impaired de Novo Lipogenesis.维生素 C 缺乏通过损害从头合成脂抑制非酒精性脂肪性肝病进展。
Am J Pathol. 2021 Sep;191(9):1550-1563. doi: 10.1016/j.ajpath.2021.05.020. Epub 2021 Jun 11.
5
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.邻苯二甲酸二（2-乙基己基）酯（MEHP）通过 JAK2/STAT5 促进脂质积累，并加重 BRL-3A 细胞的氧化应激。
Ecotoxicol Environ Saf. 2019 Nov 30;184:109611. doi: 10.1016/j.ecoenv.2019.109611. Epub 2019 Sep 3.
6
Endocrine-disrupting chemicals and fatty liver disease.内分泌干扰化学物质与脂肪肝疾病
Nat Rev Endocrinol. 2017 Aug;13(8):445-457. doi: 10.1038/nrendo.2017.42. Epub 2017 May 19.
7
Occurrence, fate, behavior and ecotoxicological state of phthalates in different environmental matrices.邻苯二甲酸酯在不同环境基质中的赋存、归趋、行为和生态毒理学状况。
Environ Sci Technol. 2015 Apr 7;49(7):4019-35. doi: 10.1021/es505233b. Epub 2015 Mar 11.
8
Oral exposure of Kunming mice to diisononyl phthalate induces hepatic and renal tissue injury through the accumulation of ROS. Protective effect of melatonin.将昆明小鼠经口暴露于邻苯二甲酸二异壬酯会通过活性氧的积累诱导肝和肾组织损伤。褪黑素的保护作用。
Food Chem Toxicol. 2014 Jun;68:247-56. doi: 10.1016/j.fct.2014.03.027. Epub 2014 Mar 29.
9
Atorvastatin and antioxidants for the treatment of nonalcoholic fatty liver disease: the St Francis Heart Study randomized clinical trial.阿托伐他汀和抗氧化剂治疗非酒精性脂肪性肝病：圣弗朗西斯心脏研究随机临床试验。
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