使用声诺维的超声造影对肝脏局灶性病变进行诊断性检测的准确性：一项系统评价和荟萃分析。
Diagnostic Test Accuracy of Contrast-Enhanced Ultrasound With Sonazoid for Assessment of Focal Liver Lesions: A Systematic Review and Meta-Analysis.
作者信息
Tang Yongqing, Sasaki Shun-Ichi, Hawley Joshua, Peillon Aurélie, Sjöström Anders, Fuentes-Alburo Adolfo, Tranquart Francois
机构信息
GE Healthcare Ltd and its Afilliates, Shanghai, China.
GE Healthcare Ltd and its Afilliates, Tokyo, Japan.
出版信息
J Clin Ultrasound. 2025 Mar-Apr;53(3):510-524. doi: 10.1002/jcu.23879. Epub 2024 Oct 23.
This meta-analysis examined the diagnostic accuracy of Sonazoid-enhanced ultrasonography (SZ-CEUS) in discriminating malignant from benign focal liver lesions (FLLs) and HCC from non-HCC FLLs. Finding relevant studies required a rigorous PubMed, EMBASE, and other database search. To distinguish malignant from benign FLLs, SZ-CEUS had a pooled sensitivity of 94% (95% CI: 0.91-0.95) and specificity of 84% (95%: 0.78-0.89). HCC distinction had 83% sensitivity and 96% specificity (95% CI: 0.80-0.85 and 0.95-0.97). SZ-CEUS accurately distinguishes malignant from benign FLLs and HCC from non-HCC lesions, especially smaller HCC lesions.
这项荟萃分析探讨了索纳造影剂增强超声（SZ-CEUS）在鉴别肝脏局灶性病变（FLL）的良恶性以及肝细胞癌（HCC）与非HCC的FLL方面的诊断准确性。查找相关研究需要对PubMed、EMBASE及其他数据库进行严格检索。为鉴别FLL的良恶性，SZ-CEUS的合并敏感度为94%（95%置信区间：0.91-0.95），特异度为84%（95%：0.78-0.89）。鉴别HCC的敏感度为83%，特异度为96%（95%置信区间：0.80-0.85和0.95-0.97）。SZ-CEUS能够准确鉴别FLL的良恶性以及HCC与非HCC病变，尤其是较小的HCC病变。
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