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人工耳蜗植入手术中脑脊液漏的回顾性分析:发生率、危险因素及结局——一项系统评价与荟萃分析

Retrospective Analysis of Cerebrospinal Gushers in Cochlear Implant Surgery: Incidence, Risk Factors, and Outcomes-A Systematic Review and Meta-analysis.

作者信息

Hazazi Mohammed, Almashharawi Eman, Alamry Saleh, Alkusayer Meshael M, Altimyat Alwaleed, Alsalamah Yazeed

机构信息

Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

King Saud Medical City, Riyadh, Saudi Arabia.

出版信息

Ear Nose Throat J. 2024 Oct 23:1455613241292195. doi: 10.1177/01455613241292195.

Abstract

Cerebrospinal fluid (CSF) gusher is a common complication experienced during cochlear implantation in patients with structural deformities in the inner ear. This study aimed to investigate the incidence of CSF gusher, risk factors, and outcomes in patients during cochlear implantation. This systematic review and meta-analysis were guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses model. Studies used in the analysis were identified through a comprehensive search in Google Scholar and PubMed. The analysis was performed using 13 retrospective studies. The incidence of CSF gusher was 5% (95% CI: 3%-9%). CSF gusher was more prevalent among patients with inner-ear malformation (IEM) than without IEM odds ratio = 63.01 (95% CI: 9.85-403.11, < .00001, = 88%). For incomplete partition (IP), CSF gusher in the IP-I group was 48% (95% CI: 25%-71%, = 0%), 19% in IP-II, 86% in IP-III, 40% in the common cavity, 26% in cochlear hypoplasia, and 27% in patients with enlarged vestibula aqueduct. The CSF gusher incidences were determined to be 5%. Patients with IEM are at increased risk of experiencing CSF gusher during cochlear implant surgery. Therefore, precise scanning reports should be produced in preoperational phase to inform proper management techniques to reduce the chances of intraoperative complications, including CSF gusher.

摘要

脑脊液喷射是内耳结构畸形患者在人工耳蜗植入过程中常见的并发症。本研究旨在调查人工耳蜗植入患者脑脊液喷射的发生率、危险因素及预后情况。本系统评价和荟萃分析遵循系统评价和荟萃分析的首选报告项目模型。通过在谷歌学术和PubMed上进行全面检索,确定分析中使用的研究。使用13项回顾性研究进行分析。脑脊液喷射的发生率为5%(95%置信区间:3%-9%)。内耳畸形(IEM)患者中脑脊液喷射比无IEM患者更普遍,优势比=63.01(95%置信区间:9.85-403.11,P<.00001,I²=88%)。对于不完全分隔(IP),IP-I组脑脊液喷射发生率为48%(95%置信区间:25%-71%,I²=0%),IP-II组为19%,IP-III组为86%,共同腔组为40%,耳蜗发育不全组为26%,前庭导水管扩大患者为27%。脑脊液喷射发生率确定为5%。IEM患者在人工耳蜗植入手术期间发生脑脊液喷射的风险增加。因此,术前应出具精确的扫描报告,以告知适当的管理技术,减少术中并发症的发生几率,包括脑脊液喷射。

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