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黑人医生纵向研究中的肥胖与高血压:梅哈里队列研究

Obesity and hypertension in a longitudinal study of black physicians: the Meharry Cohort Study.

作者信息

Neser W B, Thomas J, Semenya K, Thomas D J, Gillum R F

出版信息

J Chronic Dis. 1986;39(2):105-13. doi: 10.1016/0021-9681(86)90066-4.

Abstract

Obesity has been considered a risk factor among the precursors of essential hypertension for many years. Most related studies were general population surveys or predominantly white, male cohorts. This paper reports results of a longitudinal study of former black medical students, now practicing physicians for an average of 22.5 years. A remarkably high 43.8% were found to have developed hypertension. Fifty nine per cent of those who became obese during the study were hypertensive compared with 40% of the non-obese, 36% of those initially obese only, and 45% of those obese on both examinations. The risk ratio was 1.7 for the most obese (greater than or equal to 130% relative body weight) compared with 1.0 for the leanest group Dynamic weight change together with baseline diastolic blood pressure, were more prominent precursors than the other variables studied. Weight control would appear to be a potentially important nonpharmacologic hypertension risk reduction measure.

摘要

多年来,肥胖一直被视为原发性高血压发病先兆中的一个风险因素。大多数相关研究都是针对普通人群的调查,或者主要是白人男性队列研究。本文报告了一项针对以前的黑人医学生(现在平均从业22.5年的执业医师)的纵向研究结果。结果发现,高达43.8%的人患上了高血压。在研究期间变得肥胖的人中有59%患有高血压,相比之下,非肥胖者为40%,最初仅肥胖者为36%,两次检查时均肥胖者为45%。最肥胖者(相对体重≥130%)的风险比为1.7,而最瘦组的风险比为1.0。与所研究的其他变量相比,动态体重变化以及基线舒张压是更显著的发病先兆。体重控制似乎是一种潜在的重要非药物性降低高血压风险的措施。

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