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胎儿手术的麻醉管理:来自单中心经验(2019 - 2023年)

Anesthetic management for fetal surgery: lessons from a single-center experience (2019-2023).

作者信息

Faruja A, Idelson A, Azem K, Yosef L, Tenenbaum-Gavish K, Duvdevani N R, Fein S, Orbach-Zinger S, Gielchinsky Y

机构信息

Department of Anesthesia, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel; Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel.

Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; Fetal Medicine Center, Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikvah, Israel.

出版信息

Int J Obstet Anesth. 2025 Feb;61:104284. doi: 10.1016/j.ijoa.2024.104284. Epub 2024 Oct 9.

Abstract

BACKGROUND

Fetal surgery presents distinctive anesthetic challenges due to the need to balance maternal and fetal safety. This retrospective study evaluates the anesthetic management strategies used at a single center for various fetal interventions, including fetoscopic laser photocoagulation, fetal endoluminal tracheal occlusion, bipolar cord coagulation, and fetoscopic spina bifida repair.

METHODS

We reviewed 195 fetal procedures performed between 2019 and 2023 at Rabin Medical Center. Data collected included maternal and fetal characteristics, anesthetic techniques (spinal, combined spinal-epidural, general), intraoperative hypotension, and perioperative complications. We examined the evolution of anesthetic practice, particularly focusing on hemodynamic management and postoperative pain control.

RESULTS

Spinal anesthesia was increasingly preferred for shorter procedures such as fetoscopic laser photocoagulation and bipolar cord coagulation, while general anesthesia was used exclusively for spina bifida repair. Intraoperative hypotension was a significant issue, leading to the implementation of prophylactic phenylephrine infusions, which improved blood pressure control. A shift from volatile anesthesia to total intravenous anesthesia in spina bifida repair resulted in fewer complications, including reduced bleeding. Postoperative pain management was optimized with a multimodal approach, improving pain scores.

CONCLUSIONS

This study underscores the importance of tailoring anesthetic techniques to the specific fetal surgery. Key improvements in hypotension management, adopting total intravenous anesthesia for complex surgeries, and optimized postoperative pain control have contributed to better maternal and fetal outcomes. Ongoing reassessment and adaptation of anesthetic protocols remain critical as fetal surgery evolves.

摘要

背景

由于需要平衡母体和胎儿的安全,胎儿手术带来了独特的麻醉挑战。这项回顾性研究评估了单一中心针对各种胎儿干预措施所采用的麻醉管理策略,包括胎儿镜激光光凝术、胎儿腔内气管阻塞术、双极脐带凝固术以及胎儿镜脊柱裂修复术。

方法

我们回顾了2019年至2023年在拉宾医疗中心进行的195例胎儿手术。收集的数据包括母体和胎儿特征、麻醉技术(脊髓麻醉、腰麻-硬膜外联合麻醉、全身麻醉)、术中低血压以及围手术期并发症。我们研究了麻醉实践的演变,尤其关注血流动力学管理和术后疼痛控制。

结果

对于较短的手术,如胎儿镜激光光凝术和双极脐带凝固术,脊髓麻醉越来越受到青睐,而全身麻醉仅用于脊柱裂修复术。术中低血压是一个重要问题,促使采取预防性去氧肾上腺素输注措施,从而改善了血压控制。在脊柱裂修复术中,从挥发性麻醉转向全静脉麻醉减少了并发症,包括出血减少。通过多模式方法优化了术后疼痛管理,改善了疼痛评分。

结论

本研究强调了根据特定胎儿手术量身定制麻醉技术的重要性。在低血压管理方面的关键改进、对复杂手术采用全静脉麻醉以及优化术后疼痛控制,都有助于改善母体和胎儿的结局。随着胎儿手术的发展,持续重新评估和调整麻醉方案仍然至关重要。

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