Suppr超能文献

盆腔脏器清除术后按尿流改道类型进行的五年生活质量评估。

Five-year quality-of-life assessment by urinary diversion type after pelvic Exenterations.

作者信息

Moufarrij Sara, Dagher Christian, Filippova Olga T, Zhou Qin, Iasonos Alexia, Abu-Rustum Nadeem R, Mueller Jennifer J, Leitao Mario M, Sandhu Jaspreet, Bochner Bernard, Carter Jeanne, Chi Dennis S, Sonoda Yukio

机构信息

Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

出版信息

Gynecol Oncol. 2024 Dec;191:212-218. doi: 10.1016/j.ygyno.2024.10.016. Epub 2024 Oct 22.

Abstract

OBJECTIVE

To determine whether urinary diversion procedures performed at time of pelvic exenteration affect quality of life in patients with recurrent gynecologic malignancies.

METHODS

We performed a retrospective secondary longitudinal analysis of quality of life according to type of urinary diversion patients received. Participants completed a series of validated questionnaires at various time points. We allocated patients based on urinary diversion type to either the continent group (CD; 29 [55 %]) or noncontinent group (NCD; 24 [45 %]).

RESULTS

We noted a significant improvement in global health scores from baseline over time (time p = 0.027). Physical functioning scores showed a statistically significant difference over time (at 24 months: NCD, -4.3 [95 % CI, -14.1 to 5.4]; CD, 0.4 [95 % CI, -7.1 to 7.9]. p < 0.001). Social functioning scores were persistently higher for the CD vs NCD group at all time points but did not differ significantly between the groups at baseline (p = 0.75) or over time within the same group (time p = 0.122). Body image scores significantly decreased (reduced burden) over time for both groups (p = 0.044) and were consistently higher in the NCD vs CD group.

CONCLUSIONS

Patients experienced a return to their baseline quality of life within a year of surgery. Clinicians should prioritize and improve identifying and discussing postoperative challenges such as changes in physical and social functioning and body image.

摘要

目的

确定盆腔脏器清除术时所实施的尿流改道术是否会影响复发性妇科恶性肿瘤患者的生活质量。

方法

我们根据患者接受的尿流改道类型对生活质量进行了回顾性二次纵向分析。参与者在不同时间点完成了一系列经过验证的问卷。我们根据尿流改道类型将患者分为可控组(CD;29例[55%])或不可控组(NCD;24例[45%])。

结果

我们注意到总体健康评分随时间推移较基线有显著改善(时间p = 0.027)。身体功能评分随时间有统计学显著差异(24个月时:NCD组,-4.3[95%CI,-14.1至5.4];CD组,0.4[95%CI,-7.1至7.9]。p < 0.001)。CD组在所有时间点的社会功能评分均持续高于NCD组,但两组在基线时(p = 0.75)或同一组内随时间变化时(时间p = 0.122)差异均无统计学意义。两组的身体形象评分均随时间显著下降(负担减轻)(p = 0.044),且NCD组始终高于CD组。

结论

患者在术后一年内生活质量恢复至基线水平。临床医生应优先并更好地识别和讨论术后挑战,如身体和社会功能以及身体形象的变化。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验