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动机性访谈强化行为疗法对注意力缺陷/多动障碍青少年的三年疗效:一项基于社区的随机试验。

Three-Year Effects of Motivational Interviewing-Enhanced Behavior Therapy for Adolescents With Attention-Deficit/Hyperactivity Disorder: A Randomized Community-Based Trial.

作者信息

Sibley Margaret H, Graziano Paulo A, Coxe Stefany, Page Timothy F, Martin Pablo

机构信息

University of Washington School of Medicine and Seattle Children's Research Institute in Seattle, WA; Florida International University Herbert Wertheim College of Medicine in Miami, FL.

Florida International University in Miami, FL.

出版信息

J Am Acad Child Adolesc Psychiatry. 2024 Oct 21. doi: 10.1016/j.jaac.2024.10.009.

Abstract

OBJECTIVE

This study reports 3-year effects of a parent-teen cognitive/behavioral treatment for adolescent attention-deficit/hyperactivity disorder (ADHD), blended with Motivational Interviewing (Supporting Teens' Autonomy Daily [STAND]), vs Usual Care (UC) in 4 community clinics.

METHOD

This was a randomized clinical trial with double randomization of adolescents and therapists to STAND vs UC. Participants were 278 culturally diverse adolescents diagnosed with DSM-5 ADHD and 82 community therapists. Long-term effects on outcomes and theorized mechanisms were assessed at approximately 3 years post baseline (mean age = 16.94 years, SD = 1.69): ADHD severity (parent-rated), parent-teen conflict (parent/adolescent-rated), organization, time management, and planning skills (OTP; parent-rated), treatment and school enrollment (parent/adolescent-reported), and ADHD diagnostic persistence (clinician-determined). Therapist licensure was examined as a treatment moderator. Intent-to-treat (ITT) and per protocol analyses (n = 225; participants initiating treatment after agency intake) were conducted.

RESULTS

As in the original trial, ITT analyses indicated no long-term group by time effects. However, STAND (vs UC) led to superior long-term outcomes when therapists were licensed (22% of sample) vs unlicensed for parent-rated hyperactivity/impulsivity (d = 0.39; adolescent-rated parent-teen conflict: d = 0.27, and parent-rated OTP skills: d = 0.79). Previously reported post-treatment group differences on medication engagement were non-significant at the 3-year follow-up.

CONCLUSION

Although STAND did not outperform UC overall, group by licensure interactions indicate specific long-term impacts on ADHD symptoms, executive function skills such as OTP, and parent-teen conflict, extending this trial's acute effects and replicating previous findings. Clinicians in community settings might recommend adjunctive cognitive/behavioral treatment to adolescents with ADHD to maximize long-term outcomes. However, additional efforts are needed to facilitate effective implementation by unlicensed clinicians.

CLINICAL TRIAL REGISTRATION INFORMATION

STAND Community Trial (STAND); https://clinicaltrials.gov; NCT02694939. Long-term Follow-up of MI-based Behavioral Intervention Delivered in Community Mental Health; https://osf.io; h5w6f.

DIVERSITY & INCLUSION STATEMENT: We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented sexual and/or gender groups in science. One or more of the authors of this paper self-identifies as living with a disability. We actively worked to promote sex and gender balance in our author group. We actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our author group. While citing references scientifically relevant for this work, we also actively worked to promote sex and gender balance in our reference list. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work.

摘要

目的

本研究报告了一种针对青少年注意力缺陷多动障碍(ADHD)的家长-青少年认知/行为治疗与动机性访谈(每日支持青少年自主[STAND])相结合的方法,与4家社区诊所的常规护理(UC)相比,在3年时间里的效果。

方法

这是一项随机临床试验,青少年和治疗师被双重随机分配到STAND组或UC组。参与者包括278名被诊断患有DSM-5 ADHD的文化背景各异的青少年和82名社区治疗师。在基线后约3年(平均年龄 = 16.94岁,标准差 = 1.69)评估对结果和理论机制的长期影响:ADHD严重程度(家长评定)、家长-青少年冲突(家长/青少年评定)、组织、时间管理和计划技能(OTP;家长评定)、治疗和学校入学情况(家长/青少年报告)以及ADHD诊断持续性(临床医生确定)。将治疗师执照作为治疗调节因素进行研究。进行了意向性治疗(ITT)分析和符合方案分析(n = 225;机构接收后开始治疗的参与者)。

结果

与原始试验一样,ITT分析表明没有长期的组间随时间效应。然而,当治疗师有执照(占样本的22%)而非无执照时,STAND组(与UC组相比)在家长评定的多动/冲动方面产生了更好的长期结果(d = 0.39;青少年评定的家长-青少年冲突:d = 0.27,家长评定的OTP技能:d = 0.79)。先前报告的治疗后组间在药物治疗参与方面的差异在3年随访时不显著。

结论

尽管STAND总体上没有优于UC,但按执照情况的组间交互作用表明对ADHD症状、OTP等执行功能技能以及家长-青少年冲突有特定的长期影响,扩展了该试验的急性效应并重复了先前的发现。社区环境中的临床医生可能会向患有ADHD的青少年推荐辅助性认知/行为治疗,以实现最佳长期结果。然而,需要做出更多努力来促进无执照临床医生的有效实施。

临床试验注册信息

STAND社区试验(STAND);https://clinicaltrials.gov;NCT02694939。基于动机性访谈的行为干预在社区心理健康中的长期随访;https://osf.io;h5w6f。

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