Torres W E, Whitmire L F, Gedgaudas-McClees K, Bernardino M E
J Comput Assist Tomogr. 1986 Jan-Feb;10(1):47-50. doi: 10.1097/00004728-198601000-00009.
Computed tomography of 75 biopsy proven cirrhotic patients was analyzed volumetrically and compared with CT on 50 normal subjects in an attempt to quantitate hepatic morphologic changes specific for cirrhosis. Our data show that the mean percentage of the total liver volume occupied by the right hepatic lobe decreased by 15.2% (p less than 0.0001) and the mean percentage of the total liver volume occupied by the medial segment of the left lobe decreased in volume by 10.9% (p less than 0.09) when compared with normals. Concomitantly, the mean percentage of the total liver volume occupied by the caudate lobe increased by 192% (p less than 0.0001) and the mean percentage of the total liver volume occupied by the lateral segment of the left lobe increased by 55.6% (p less than 0.0001). This increase in the volume of the lateral segment of the left lobe and decrease in the volume of the medial segment of the left lobe have not been described previously. The cirrhotic patients were divided according to etiology of their disease: alcoholic or nonalcoholic. No statistically significant difference was found in the morphologic changes based on etiology when the data were examined using analysis of variants.
对75例经活检证实为肝硬化患者的计算机断层扫描进行了容积分析，并与50名正常受试者的CT进行比较，试图对肝硬化特有的肝脏形态学变化进行量化。我们的数据显示，与正常人相比，右肝叶占肝脏总体积的平均百分比下降了15.2%（p<0.0001），左叶内侧段占肝脏总体积的平均百分比下降了10.9%（p<0.09）。同时，尾状叶占肝脏总体积的平均百分比增加了192%（p<0.0001），左叶外侧段占肝脏总体积的平均百分比增加了55.6%（p<0.0001）。左叶外侧段体积增加和左叶内侧段体积减少的情况此前尚未见报道。根据疾病病因将肝硬化患者分为酒精性或非酒精性。当使用方差分析检查数据时，未发现基于病因的形态学变化有统计学显著差异。
