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癌症化疗期间的运动:一项系统评价

Exercise During Chemotherapy for Cancer: A Systematic Review.

作者信息

Walker R C, Pezeshki P, Barman S, Ngan S, Whyte G, Lagergren J, Gossage J, Kelly M, Baker C, Knight W, West M A, Davies A R

机构信息

Guy's & St Thomas' Oesophago-gastric Centre, London, UK.

School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.

出版信息

J Surg Oncol. 2024 Dec;130(8):1725-1736. doi: 10.1002/jso.27845. Epub 2024 Oct 23.

Abstract

Exercise prehabilitation may improve the tolerance and effectiveness of anticancer treatments such as chemotherapy. This systematic review assesses the impact of exercise on chemotherapy outcomes and identifies research priorities. Nineteen studies (1418 patients) were reviewed, including 11 randomised controlled trials and eight observational studies. Exercise led to improvements in body composition, fitness, strength and quality of life (QoL) across studies. Exercise can be safely and effectively delivered during chemotherapy. Limited standardisation and small sample sizes highlight the need for larger, better-designed studies to optimise this low-cost intervention.

摘要

运动预康复可能会提高化疗等抗癌治疗的耐受性和有效性。本系统评价评估了运动对化疗结果的影响,并确定了研究重点。共纳入19项研究(1418例患者),包括11项随机对照试验和8项观察性研究。各项研究结果显示,运动可改善身体成分、体能、力量和生活质量(QoL)。化疗期间可以安全有效地进行运动。由于标准化程度有限和样本量较小,因此需要开展规模更大、设计更优的研究,以优化这种低成本干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d10/11849706/1e5a7dcd8b77/JSO-130-1725-g001.jpg

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