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隐球菌样Sweet综合征:一例报告

Cryptococcoid Sweet syndrome: a case report.

作者信息

Volonté Martina, Fiandrino Giacomo, Vassallo Camilla, Barruscotti Stefania, Giorgini Chiara, Tomasini Carlo Francesco, Brazzelli Valeria

机构信息

Institute of Dermatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Pathology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

出版信息

Front Med (Lausanne). 2024 Oct 9;11:1468712. doi: 10.3389/fmed.2024.1468712. eCollection 2024.

Abstract

Cryptococcoid Sweet syndrome (cSS) is a recently described clinical and histological variant of Sweet syndrome (SS). Its cutaneous presentation is similar to the classical form of SS but it includes atypical findings, such as capsular and yeast-like structures on microscopy that are reminiscent of species. However, in cSS, fungal staining and cultural examination are negative, whereas myeloperoxidase (MPO) staining on biopsy specimens is typically positive. Due to the rarity and the diagnostic challenge represented by this disease, its extracutaneous involvement, and the latency in its diagnosis, this condition is frequently associated with poor prognosis. In this study, we report the case of a cSS patient with a positive outcome.

摘要

隐球菌样Sweet综合征(cSS)是最近描述的Sweet综合征(SS)的一种临床和组织学变异型。其皮肤表现与经典型SS相似,但包括非典型表现,如显微镜下可见的荚膜样和酵母样结构,让人联想到某些菌种。然而,在cSS中,真菌染色和培养检查均为阴性,而活检标本上的髓过氧化物酶(MPO)染色通常为阳性。由于这种疾病罕见、诊断具有挑战性、存在皮肤外受累情况以及诊断延迟,这种情况常与预后不良相关。在本研究中,我们报告了一例预后良好的cSS患者病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f73/11496249/a92f47579aec/fmed-11-1468712-g001.jpg

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