Maisat Wiriya, Lapmahapaisan Saowaphak
Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
J Thorac Dis. 2024 Sep 30;16(9):5936-5945. doi: 10.21037/jtd-24-771. Epub 2024 Sep 19.
Tachyarrhythmias are a common and significant complication following surgery for adult congenital heart disease (CHD), adversely affecting morbidity. This study aimed to assess the incidence, characteristics, and risk factors of early postoperative tachyarrhythmias in adults undergoing CHD surgery.
We conducted a retrospective cohort study at Siriraj Hospital, Bangkok, Thailand, including 311 adult patients who underwent elective CHD surgeries from March 2013 to November 2020. We analyzed demographic and surgical data, focusing on new-onset tachyarrhythmias requiring interventions such as antiarrhythmic drugs or cardioversion.
The patient cohort had a median age of 34 years (range, 18-78 years), with 34.7% male, predominantly diagnosed with atrial and ventricular septal defects (54.7%), and severe pulmonary regurgitation post-tetralogy of Fallot repair (22.2%). Postoperative tachyarrhythmias occurred in 12.9% of patients, with atrial fibrillation (AF; 67.5%) and atrial flutter (AFL; 14.5%) being the most frequent. Independent risk factors for tachyarrhythmias included older age [adjusted odds ratio (OR) =1.26 per 5-year increment; 95% confidence interval (CI): 1.12-1.42; P<0.001] and left atrial enlargement (adjusted OR=2.78; 95% CI: 1.31-5.85; P=0.007).
Early postoperative tachyarrhythmias are prevalent in adults undergoing CHD surgery, with advanced age and left atrial enlargement as significant risk factors. These findings underscore the importance of early detection and management of septal defects and advocate for enhanced screening and healthcare strategies to reduce postoperative complications in this population.
快速性心律失常是成人先天性心脏病(CHD)手术后常见且严重的并发症,对发病率有不利影响。本研究旨在评估接受CHD手术的成人术后早期快速性心律失常的发生率、特征和危险因素。
我们在泰国曼谷诗里拉吉医院进行了一项回顾性队列研究,纳入了2013年3月至2020年11月期间接受择期CHD手术的311例成年患者。我们分析了人口统计学和手术数据,重点关注需要抗心律失常药物或心脏复律等干预措施的新发快速性心律失常。
患者队列的中位年龄为34岁(范围18 - 78岁),男性占34.7%,主要诊断为房间隔和室间隔缺损(54.7%),法洛四联症修复术后严重肺动脉反流(22.2%)。12.9%的患者发生术后快速性心律失常,其中房颤(AF;67.5%)和房扑(AFL;14.5%)最为常见。快速性心律失常的独立危险因素包括年龄较大[调整优势比(OR)=每增加5岁为1.26;95%置信区间(CI):1.12 - 1.42;P<0.001]和左心房扩大(调整OR = 2.78;95% CI:1.31 - 5.85;P = 0.007)。
接受CHD手术的成人术后早期快速性心律失常很常见,高龄和左心房扩大是重要危险因素。这些发现强调了早期发现和处理间隔缺损的重要性,并提倡加强筛查和医疗保健策略以减少该人群的术后并发症。