Bargaje Shubham N, Ramteke Harshal, Tare Aishwarya K
Surgery, N.K.P. Salve Institute of Medical Sciences and Research Center, Nagpur, IND.
Cureus. 2024 Sep 22;16(9):e69955. doi: 10.7759/cureus.69955. eCollection 2024 Sep.
Intracholecystic papillary neoplasm (ICPN) is a mass-forming, noninvasive epithelial premalignant neoplasm arising from the gallbladder mucosal lining and projecting into the lumen of the gallbladder. It is potentially fatal and if left untreated can progress to invasive gallbladder carcinoma. Incidentally ICPN is found on imaging or during postoperative histological evaluation and is likely to be missed preoperatively. We present a rare case of ICPN in a 70-year-old female patient who was admitted with complaints of pain in the right hypochondrium since one month and was postoperatively diagnosed with ICPN through histopathological examination. We discuss the need for early intervention in gallbladder polypoidal masses to prevent the conversion of benign or preinvasive tumors to malignancy.
胆囊内乳头状瘤（ICPN）是一种形成肿块的、非侵袭性的上皮性癌前肿瘤，起源于胆囊黏膜层并向胆囊腔内突出。它有潜在致命性，如果不治疗可能进展为侵袭性胆囊癌。ICPN偶然在影像学检查或术后组织学评估中被发现，术前很可能被漏诊。我们报告一例罕见的ICPN病例，患者为70岁女性，因右季肋部疼痛1个月入院，术后经组织病理学检查诊断为ICPN。我们讨论了对胆囊息肉样肿物进行早期干预以防止良性或癌前肿瘤转变为恶性肿瘤的必要性。
