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拉丁美洲某单一国家一个中心的失代偿性心力衰竭:ICARUS注册研究中前1595例病例的研究结果

Decompensated heart failure in a single center of a Latin American country: findings from the first 1595 cases in the ICARUS registry.

作者信息

Rojas Lyda Z, Gómez-Ochoa Sergio A, Rodríguez Jaime A, García-Rueda Karen A, Torres-Bustamante Angela M, Botero Daniel R, Cantillo-Reines María, Serrano-García Angie Y, Jurado Adriana M, Castro Kelly J, Pinilla Katerine, Mendoza-Quiñonez Angie C, Vasquez Nelly J, Alvarez Yeinmy Y, Rojas Maribel, Ortega-Solano Diana M, Sanabria Yesenia, Vargas-Sanabria Angelica, Cáceres Aura M, Bohorquez-Hernández Paula S, Portillo Carlos, Echeverría Luis E

机构信息

Nursing Research and Knowledge Development Group (GIDCEN-FCV), Research Center, Fundación Cardiovascular de Colombia, Floridablanca, Colombia.

Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.

出版信息

Arch Cardiol Mex. 2024 Oct 24;95(1):42-48. doi: 10.24875/ACM.24000020.

Abstract

OBJECTIVE

Describe the methodological aspects, sociodemographic, and clinical characteristics of patients hospitalized with acute decompensated heart failure (ADHF) and their short-term outcomes.

METHODS

Prospective cohort of patients with ADHF from the emergency service of the cardiovascular center. Descriptive statistics were used to synthesize sociodemographic characteristics, clinical characteristics during hospitalization, and outcomes.

RESULTS

1595 patients with ADHF. The median age was 68 years (Q1 = 58; Q3 = 76), and 69.28% were men. The median hospital stay was 6 days (Q1 = 4; Q3 = 11), with an cumulative incidence for re-hospitalization at 30 days of 8.70% (95% CI 7.18-10.40%), in-hospital mortality cumulative incidence of 4.33% (95% CI 3.38-5.44%), and a median change in the quality-of-life score Minnesota Living with Heart Failure at 30 days of -20 points (Q1 = -37; Q3 = -5). At discharge, all patients had a percentage > 70% of the use of quadruple neurohormonal blockade therapy.

CONCLUSION

Institutional aCute decompensAted HeaRt FailUre RegiStry (ICARUS) is one of the first studies in Latin America to demonstrate the importance of characterizing the population with ADHF and the adherence to heart failure guidelines may have influenced the favorable clinical outcomes.

摘要

目的

描述急性失代偿性心力衰竭(ADHF)住院患者的方法学方面、社会人口统计学和临床特征及其短期结局。

方法

对心血管中心急诊科的ADHF患者进行前瞻性队列研究。采用描述性统计方法综合社会人口统计学特征、住院期间的临床特征和结局。

结果

1595例ADHF患者。中位年龄为68岁(第一四分位数Q1 = 58;第三四分位数Q3 = 76),69.28%为男性。中位住院时间为6天(Q1 = 4;Q3 = 11),30天再住院累积发生率为8.70%(95%可信区间7.18 - 10.40%),住院死亡率累积发生率为4.33%(95%可信区间3.38 - 5.44%),30天明尼苏达心力衰竭生活质量评分的中位变化为-20分(Q1 = -37;Q3 = -5)。出院时,所有患者四重神经激素阻断治疗的使用率均>70%。

结论

机构急性失代偿性心力衰竭注册研究(ICARUS)是拉丁美洲最早证明对ADHF人群进行特征描述的重要性的研究之一,并且遵循心力衰竭指南可能影响了良好的临床结局。

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