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住院患者常规实验室检查的成本和收益:医源性贫血和未诊断的急性肾损伤。

Costs and benefits of routine labs in hospital patients: iatrogenic anaemia and undiagnosed acute kidney injury.

机构信息

Internal Medicine, University of Kentucky Medical Center, Lexington, Kentucky, USA

出版信息

BMJ Open Qual. 2024 Oct 23;13(4):e002884. doi: 10.1136/bmjoq-2024-002884.

DOI:10.1136/bmjoq-2024-002884
PMID:39448089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11499769/
Abstract

IMPORTANCE

Guidelines recommend avoiding unnecessary laboratory tests to minimise risks of anaemia in hospitalised patients as well as reduce costs, but there are costs to skipping routine labs including missing acute kidney injury.

OBJECTIVE

Quantify the costs and benefits of routine labs in dollar costs as well as mortality.

EVIDENCE REVIEW

This is a retrospective analysis of 48 204 admissions at University of Kentucky Hospitals and simulates different strategies for skipping labs.

FINDINGS

In a simplified estimate of pure dollar costs, the costs of daily labs appear to outweigh the costs of missing acute kidney injury.

CONCLUSIONS AND RELEVANCE

In both dollar costs and the number of patients with mortality effects, the benefits of randomly skipping labs appear to significantly outweigh the costs, but the costs are not insignificant.

摘要

重要性

指南建议避免不必要的实验室检查,以尽量减少住院患者贫血的风险并降低成本,但跳过常规实验室检查会有一些成本,包括漏诊急性肾损伤。

目的

以美元成本和死亡率量化常规实验室检查的成本和收益。

证据综述

这是对肯塔基大学医院 48204 例住院患者的回顾性分析,并模拟了跳过实验室检查的不同策略。

发现

在每日实验室检查的纯美元成本的简化估计中,实验室检查的成本似乎超过了漏诊急性肾损伤的成本。

结论和相关性

在美元成本和死亡率影响的患者数量方面,随机跳过实验室检查的收益似乎明显超过成本,但成本并非微不足道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/fe3ac6d9cab0/bmjoq-13-4-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/11ebc3665d69/bmjoq-13-4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/0ce3c196bfc5/bmjoq-13-4-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/2dd04d4e150d/bmjoq-13-4-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/e5fa6a0d78c8/bmjoq-13-4-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/fe3ac6d9cab0/bmjoq-13-4-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/11ebc3665d69/bmjoq-13-4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/0ce3c196bfc5/bmjoq-13-4-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/2dd04d4e150d/bmjoq-13-4-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/e5fa6a0d78c8/bmjoq-13-4-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b0/11499769/fe3ac6d9cab0/bmjoq-13-4-g005.jpg

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Patient Blood Management: Recommendations From the 2018 Frankfurt Consensus Conference.患者血液管理:2018 年法兰克福共识会议推荐意见。
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Incidence, Predictors, and Outcomes of Hospital-Acquired Anemia.医院获得性贫血的发病率、预测因素及结局
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Hospital-acquired anemia: prevalence, outcomes, and healthcare implications.医院获得性贫血:患病率、结局及对医疗保健的影响。
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KDIGO clinical practice guidelines for acute kidney injury.改善全球肾脏病预后组织(KDIGO)急性肾损伤临床实践指南
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Incidence, correlates, and outcomes of acute, hospital-acquired anemia in patients with acute myocardial infarction.急性心肌梗死患者急性医院获得性贫血的发病率、相关因素及预后
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Estimating GFR using the CKD Epidemiology Collaboration (CKD-EPI) creatinine equation: more accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions.使用慢性肾脏病流行病学协作组(CKD-EPI)肌酐方程估算肾小球滤过率(GFR):GFR估算更准确,慢性肾脏病患病率估算更低,风险预测更优。
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Acute kidney injury increases risk of ESRD among elderly.急性肾损伤会增加老年人患终末期肾病的风险。
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Acute kidney injury, mortality, length of stay, and costs in hospitalized patients.住院患者的急性肾损伤、死亡率、住院时间及费用
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