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认知衰弱在中国老年人中的流行情况及影响因素:系统回顾和荟萃分析。

Prevalence and influencing factors of cognitive frailty among Chinese older adults: A systematic review and meta-analysis.

机构信息

Department of Psychology, School of Philosophy, Wuhan University, Wuhan, Hubei, China.

Department of Nursing, Hubei College of Chinese Medicine, Jingzhou, Hubei, China.

出版信息

Int J Nurs Pract. 2024 Dec;30(6):e13306. doi: 10.1111/ijn.13306. Epub 2024 Oct 24.

DOI:10.1111/ijn.13306
PMID:39448383
Abstract

AIMS

Cognitive frailty refers to the coexistence of physical frailty and cognitive impairment in older adults, without a concurrent diagnosis of Alzheimer's disease or other dementias. This review aims to evaluate the prevalence of CF subtypes and identify influencing factors among Chinese older adults.

METHODS

The following databases were searched: PubMed/Medline, Embase, Cochrane Library, WOS, PsycINFO and CNKI et al (1 January 2001 to 20 October 2022). The risk of bias was assessed using the Agency for Healthcare Research and Quality Evidence-based Practice Center Methods Guide. Stata 17.0 software was used to pool the prevalence of cognitive frailty, and the pooled odds ratio and 95% CI of the influencing factors were calculated.

RESULTS

The meta-analysis (56 studies and 80,320 participants) revealed the following prevalence rates: CF (18.9%), reversible CF (19.5%), potentially reversible CF (17.5%), CF in community-dwelling older adults (14.3%), CF in nursing homes (22.7%) and CF in older inpatients (25.2%). Influential factors identified included age, gender, education, nutrition, depression, exercise, sleep and comorbidity.

CONCLUSIONS

The prevalence of CF among Chinese older adults is notably high, and it probably underestimates the prevalence of reversible cognitive frailty. It is crucial to encourage adherence to healthy behaviours, as it can effectively reduce and delay the onset of cognitive frailty.

摘要

目的

认知脆弱是指老年人同时存在身体脆弱和认知障碍,但没有阿尔茨海默病或其他痴呆症的诊断。本综述旨在评估中国老年人认知脆弱亚型的患病率,并确定其影响因素。

方法

检索了以下数据库:PubMed/Medline、Embase、Cochrane 图书馆、WOS、PsycINFO 和中国知网等(2001 年 1 月 1 日至 2022 年 10 月 20 日)。使用美国医疗保健研究与质量循证实践中心方法指南评估偏倚风险。使用 Stata 17.0 软件汇总认知脆弱的患病率,并计算影响因素的汇总优势比和 95%置信区间。

结果

荟萃分析(56 项研究和 80320 名参与者)显示以下患病率:认知脆弱(18.9%)、可逆认知脆弱(19.5%)、潜在可逆认知脆弱(17.5%)、社区居住老年人认知脆弱(14.3%)、养老院老年人认知脆弱(22.7%)和住院老年人认知脆弱(25.2%)。确定的影响因素包括年龄、性别、教育、营养、抑郁、运动、睡眠和共病。

结论

中国老年人认知脆弱的患病率明显较高,可能低估了可逆认知脆弱的患病率。鼓励老年人坚持健康行为至关重要,因为这可以有效减少和延迟认知脆弱的发生。

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