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口腔表现与溃疡性结肠炎患者疾病严重程度的相关性。

Association of oral manifestations with severity of the disease in ulcerative colitis patients.

机构信息

Dental Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

Department of Oral and Maxillofacial Medicine, School of Dentistry, Golestan University of Medical Sciences, PO Box 4916953363, Gorgan, Iran.

出版信息

BMC Gastroenterol. 2024 Oct 24;24(1):378. doi: 10.1186/s12876-024-03472-9.

Abstract

OBJECTIVE

Inflammatory bowel diseases (IBD), such as Crohn's disease (CD) and ulcerative colitis (UC), are chronic conditions primarily affecting the intestines. This study aims to identify the nature and frequency of oral symptoms and signs in patients with ulcerative colitis and to explore the connection between these complications and the activity of the disease.

METHODS

This descriptive-analytical study involved ulcerative colitis patients who visited the gastroenterology clinic at Shahid Sayad Shirazi Hospital in Gorgan, along with an equal number of healthy companions as a control group in 2019. A gastroenterology internist assessed the disease severity through clinical examination and a simple clinical disease activity index for colitis patients. The collected data were then analyzed statistically using SPSS version 19.

RESULTS

The average age of patients in the case group was 41.84 ± 11.66 years, while in the control group it was 40.43 ± 12.67 years. There was a significant correlation between difficulty swallowing, burning sensation in the mouth, vomiting, acidic taste, the presence of oral ulcers, and a coated tongue with the severity of disease activity (p < 0.05). However, no significant relationship was found between other variables and the severity of disease activity (p > 0.05).

CONCLUSION

The results of this study confirm that as the severity of ulcerative colitis increases, the occurrence of oral lesions also rises, particularly during severe disease activity. Among oral symptoms, dry mouth had the highest incidence, followed by bad breath and changes in taste. The most common oral lesions observed were a coated tongue, grooved tongue, and oral ulcers, respectively.

摘要

目的

炎症性肠病(IBD),如克罗恩病(CD)和溃疡性结肠炎(UC),是主要影响肠道的慢性疾病。本研究旨在确定溃疡性结肠炎患者口腔症状和体征的性质和频率,并探讨这些并发症与疾病活动之间的关系。

方法

本描述性分析研究于 2019 年在戈尔甘沙希德赛义德希拉齐医院的胃肠病学诊所招募了溃疡性结肠炎患者,并招募了与患者数量相等的健康对照者。一名胃肠病学住院医师通过临床检查和简单的结肠炎临床疾病活动指数评估患者的疾病严重程度。然后使用 SPSS 版本 19 对收集的数据进行统计学分析。

结果

病例组患者的平均年龄为 41.84±11.66 岁,而对照组为 40.43±12.67 岁。吞咽困难、口腔烧灼感、呕吐、酸味、口腔溃疡和舌苔与疾病活动严重程度之间存在显著相关性(p<0.05)。然而,其他变量与疾病活动严重程度之间没有显著关系(p>0.05)。

结论

本研究结果证实,随着溃疡性结肠炎的严重程度增加,口腔病变的发生也会增加,尤其是在疾病活动严重时。在口腔症状中,口干的发生率最高,其次是口臭和味觉改变。观察到的最常见的口腔病变分别是舌苔、沟纹舌和口腔溃疡。

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本文引用的文献

1
Bowel Urgency in Ulcerative Colitis: Current Perspectives and Future Directions.
Am J Gastroenterol. 2023 Nov 1;118(11):1940-1953. doi: 10.14309/ajg.0000000000002404. Epub 2023 Jun 12.
2
A Systematic Review of the Role of Diet in Ulcerative Colitis.
Cureus. 2023 May 22;15(5):e39350. doi: 10.7759/cureus.39350. eCollection 2023 May.
3
Patient education interventions for the management of inflammatory bowel disease.
Cochrane Database Syst Rev. 2023 May 4;5(5):CD013854. doi: 10.1002/14651858.CD013854.pub2.
5
Oral manifestations serve as potential signs of ulcerative colitis: A review.
Front Immunol. 2022 Sep 29;13:1013900. doi: 10.3389/fimmu.2022.1013900. eCollection 2022.
8
Association of oral manifestations in ulcerative colitis: A pilot study.
J Oral Maxillofac Pathol. 2018 May-Aug;22(2):199-203. doi: 10.4103/jomfp.JOMFP_223_16.
9
Oral manifestations of inflammatory bowel disease.
J Biol Regul Homeost Agents. 2017 Jul-Sep;31(3):817-821.
10
Ulcerative colitis.
Lancet. 2017 Apr 29;389(10080):1756-1770. doi: 10.1016/S0140-6736(16)32126-2. Epub 2016 Dec 1.

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