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基因组编辑时代的植物保护:机遇与挑战。

Plant conservation in the age of genome editing: opportunities and challenges.

机构信息

School of Grassland Science, Beijing Forestry University, Beijing, 100083, China.

Department of Biological Sciences, Chungnam National University, Daejeon, 34134, South Korea.

出版信息

Genome Biol. 2024 Oct 24;25(1):279. doi: 10.1186/s13059-024-03399-0.

Abstract

Numerous plant taxa are threatened by habitat destruction or overexploitation. To overcome these threats, new methods are urgently needed for rescuing threatened and endangered plant species. Here, we review the genetic consequences of threats to species populations. We highlight potential advantages of genome editing for mitigating negative effects caused by new pathogens and pests or climate change where other approaches have failed. We propose solutions to protect threatened plants using genome editing technology unless absolutely necessary. We further discuss the challenges associated with genome editing in plant conservation to mitigate the decline of plant diversity.

摘要

许多植物类群受到栖息地破坏或过度开发的威胁。为了克服这些威胁,迫切需要新的方法来拯救濒危植物物种。在这里,我们回顾了物种种群受到威胁的遗传后果。我们强调了基因组编辑在减轻新的病原体和害虫或其他方法失败的气候变化造成的负面影响方面的潜在优势。我们提出了使用基因组编辑技术保护濒危植物的解决方案,除非绝对必要。我们进一步讨论了与植物保护相关的基因组编辑挑战,以减轻植物多样性的下降。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1753/11515576/0e60f5a5da4a/13059_2024_3399_Fig1_HTML.jpg

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