Dervenis Nikolaos, Vagiakis Iordanis, Papadopoulou Elena P, Dervenis Panagiotis, Sandinha Teresa
Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool L69 7ZX, UK.
Department of Ophthalmology, Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Vision (Basel). 2024 Oct 19;8(4):63. doi: 10.3390/vision8040063.
We are presenting a new method for the treatment of large macular holes (MHs) with the use of an inverted flap consisting of both internal limiting membrane (ILM) and epiretinal proliferation (EP). A prospective interventional case series was conducted from September 2021 to January 2023. MH patients with coexistent EP visualized preoperatively in macula optical coherence tomography and with a MHs minimum linear diameter larger than 400 microns underwent standard pars plana vitrectomy with the creation of an inverted petaloid flap (consisting of both ILM and EP) and gas tamponade. Sixteen eyes were included in our case series. MHs closure was successful in all the eyes with a single procedure. The preoperative minimum linear diameter was 707.63 (±164.02 μm), and the preoperative best corrected visual acuity was 1.11 ± 0.52. The postoperative BCVA was 0.51 ± 0.20 ( = 0.01) at 6 weeks postoperatively, and the final BCVA was 0.45 ± 0.20 ( = 0.008). EP can be safely combined with ILM for the creation of an inverted, petaloid flap to cover and facilitate the closure of large MHs.
我们正在介绍一种治疗大黄斑裂孔（MH）的新方法，即使用由内界膜（ILM）和视网膜前增殖（EP）组成的倒置瓣。从2021年9月至2023年1月进行了一项前瞻性介入病例系列研究。术前在黄斑光学相干断层扫描中可见并存EP且MH最小线性直径大于400微米的MH患者，接受了标准的平坦部玻璃体切除术，制作了一个倒置花瓣状瓣（由ILM和EP组成）并进行了气体填充。我们的病例系列纳入了16只眼。所有眼睛单次手术MH均成功闭合。术前最小线性直径为707.63（±164.02μm），术前最佳矫正视力为1.11±0.52。术后6周时最佳矫正视力（BCVA）为0.51±0.20（P = 0.01），最终BCVA为0.45±0.20（P = 0.008）。EP可安全地与ILM联合用于制作倒置的花瓣状瓣，以覆盖并促进大MH的闭合。
