Kahn Geoffrey D, Lockhart Elizabeth, Simon Gregory E, Owen-Smith Ashli A, Rossom Rebecca C, Beck Arne L, Lynch Frances L, Daida Yihe G, Lu Christine Y, Waring Stephen, Yeh Hsueh-Han, Ahmedani Brian K
Center for Health Policy & Health Services Research, Henry Ford Health, Detroit, Michigan, USA.
Kaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
Transgend Health. 2024 Oct 9;9(5):454-458. doi: 10.1089/trgh.2022.0110. eCollection 2024 Oct.
We assessed the association between gender identity disorder (GID) diagnosis and suicide in a retrospective case-control study (=300,364) from nine health care systems between 2000 and 2015. Adjusting for age and sex, the odds ratio for GID was 18.6 (95% confidence interval 7.0-49.5). Adjusting additionally for comorbid psychiatric diagnoses, the odds ratio was 4.75 (1.78-12.68), higher than depressive (3.96, 3.64-4.31), alcohol use (3.42, 3.04-3.84), bipolar (2.42, 2.10-2.80), and psychotic disorders (1.44, 1.22-1.70). These U.S. data support prior research demonstrating increased suicide risk among patients with diagnosed GID, who may benefit from targeted screening and intervention within health care systems.
在一项2000年至2015年期间来自九个医疗保健系统的回顾性病例对照研究(n = 300,364)中,我们评估了性别认同障碍(GID)诊断与自杀之间的关联。在对年龄和性别进行调整后,GID的优势比为18.6(95%置信区间7.0 - 49.5)。在进一步对共病精神疾病诊断进行调整后,优势比为4.75(1.78 - 12.68),高于抑郁症(3.96,3.64 - 4.31)、酒精使用障碍(3.42,3.04 - 3.84)、双相情感障碍(2.42,2.10 - 2.80)和精神障碍(1.44,1.22 - 1.70)。这些美国数据支持了先前的研究,该研究表明,被诊断为GID的患者自杀风险增加,他们可能会从医疗保健系统内的针对性筛查和干预中受益。