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优化二极管激光与药物疗法在口腔黏膜下纤维化管理中的协同作用:一例报告

Optimizing the Synergistic Role of Diode Laser and Drug Therapies in the Management of Oral Submucous Fibrosis: A Case Report.

作者信息

Varma Siddhartha, Karambelkar Mugdha V, Suragimath Girish, Yavagal Chandrashekar, Mangalekar Sachin B, Zope Sameer A, Gangavati Rashmi

机构信息

Department of Periodontology, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.

Department of Pedodontics and Preventive Dentistry, Bapuji Dental College and Hospital, Davangere, IND.

出版信息

Cureus. 2024 Sep 23;16(9):e70028. doi: 10.7759/cureus.70028. eCollection 2024 Sep.

Abstract

Oral submucous fibrosis (OSMF) is one of the most common precancerous conditions of the oral mucosa involving any part of the oral cavity resulting in tissue scarring, dysphagia, and trismus. Habits of chewing areca nut, tobacco, and pan masala and smoking have revealed a strong association with the occurrence of OSMF. Due to its high morbidity and high malignant transformation rate (MTR), continuous efforts have been made to develop effective treatment options. Based on the stage of the disease, various treatment modalities such as medical and surgical therapies are available, each with its own set of advantages and disadvantages. Photobiomodulation (PBM) is an emerging minimally invasive therapy that can be utilized to treat OSMF through its anti-inflammatory and analgesic effects. With the advent of dual-wavelength diode lasers, the current case report focuses on a novel treatment strategy for managing OSMF in combination with pharmacological and oral physiotherapy to achieve optimal results.

摘要

口腔黏膜下纤维化(OSMF)是口腔黏膜最常见的癌前病变之一,可累及口腔的任何部位,导致组织瘢痕形成、吞咽困难和牙关紧闭。咀嚼槟榔、烟草、印度传统嚼块以及吸烟的习惯已显示出与OSMF的发生密切相关。由于其高发病率和高恶变率(MTR),人们一直在不断努力开发有效的治疗方案。根据疾病阶段,有多种治疗方式可供选择,如药物治疗和手术治疗,每种方式都有其自身的优缺点。光生物调节(PBM)是一种新兴的微创治疗方法,可通过其抗炎和镇痛作用用于治疗OSMF。随着双波长二极管激光器的出现,本病例报告重点关注一种结合药物治疗和口腔物理治疗来管理OSMF的新治疗策略,以实现最佳效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e187/11499076/f6aed3db448b/cureus-0016-00000070028-i01.jpg

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