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Bis(aminoalkyl)cyclopropenylidene (BAC)-Catalyzed Intramolecular Annulation of 2-(2-Formylaryl)-aryl-Substituted -Quinone Methides to 9-Phenanthrol Derivatives.

作者信息

Ranga Pavit K, Ahmad Feroz, Fatma Shaheen, Kumar Arun, Baranwal Divyanshu, Vijaya Anand Ramasamy

机构信息

Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, Knowledge City, SAS Nagar, Manauli (PO), Mohali,Punjab140306, India.

出版信息

J Org Chem. 2024 Nov 15;89(22):16697-16710. doi: 10.1021/acs.joc.4c01993. Epub 2024 Oct 25.

DOI:10.1021/acs.joc.4c01993
PMID:39451066
Abstract

This article describes a bis(aminoalkyl)cyclopropenylidene (BAC)-catalyzed intramolecular annulation of strategically designed 2-(2-formylaryl)-phenyl-substituted -quinone methides (QMs) to access 9-phenanthrol derivatives and related carbocycles. In addition, the synthetic utility of this methodology has been demonstrated in the synthesis of the seven-membered carbocyclic core of resveratrol-based natural products (±)-shoreaphenol and (±)-malibatol A.

摘要

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