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膝关节骨关节炎的疼痛管理:来自意大利患者和医生在线探索性调查的见解

Pain Management in Knee Osteoarthritis: Insights from an Exploratory Online Survey of Italian Patients and Physicians.

作者信息

Iolascon Giovanni, Migliore Alberto, Beretta Giovanna, Bernetti Andrea, Bortolotti Roberto, Celano Antonella, Giarratano Antonino, Marinangeli Franco, Momoli Alberto, Sebastiani Gian Domenico, Tomasini Andrea, Tonolo Silvia, Madotto Fabiana, Di Martino Alberto, Natoli Silvia

机构信息

Department of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

Rheumatology Unit, San Pietro Fatebenefratelli Hospital, 00189 Rome, Italy.

出版信息

Healthcare (Basel). 2024 Oct 18;12(20):2077. doi: 10.3390/healthcare12202077.

Abstract

BACKGROUND

In Italy, knee osteoarthritis (KOA) accounts for over 5 million prevalent cases and requires long-term multidisciplinary management. The most frequent KOA symptom is pain. The aim of the survey is to provide a national overview of the current management of moderate-to-severe pain associated with KOA from both clinicians' and patients' perspectives.

METHODS

An exploratory qualitative survey was conducted in Italy between July and October 2023. The survey participants were members of four national scientific societies and two patient associations who were invited to participate via email and given an online questionnaire. Questions included a mix of single and multiple responses and scalar items.

RESULTS

In total, 1473 clinicians and 150 patients with KOA completed the questionnaire. Patients rated knee pain as both the most burdensome symptom and the most frequent reason for treatment dissatisfaction and seeking consultation. One in two patients declared that they were unsatisfied/little satisfied with the current prescribed analgesic treatments. The clinicians surveyed preferentially prescribed intra-articular hyaluronic acid, oral non-steroidal anti-inflammatory drugs/paracetamol, non-pharmacological intervention, and intra-articular corticosteroids. The clinicians' selection of analgesic therapy often failed to adequately meet patients' expectations for pain relief.

CONCLUSIONS

Our findings highlight the current unmet needs of patients with KOA in Italy and call for new approaches to effectively optimize the management of KOA-associated pain.

摘要

背景

在意大利,膝关节骨关节炎(KOA)的患病率超过500万例,需要长期的多学科管理。KOA最常见的症状是疼痛。本调查的目的是从临床医生和患者的角度,对当前KOA相关中重度疼痛的管理提供全国性概述。

方法

2023年7月至10月在意大利进行了一项探索性定性调查。调查参与者是四个国家科学协会和两个患者协会的成员,他们通过电子邮件被邀请参与并收到一份在线问卷。问题包括单项和多项回答以及标量项目。

结果

共有1473名临床医生和150名KOA患者完成了问卷。患者将膝关节疼痛评为最沉重的症状,也是治疗不满意和寻求咨询的最常见原因。每两名患者中就有一名表示对当前开具的止痛治疗不满意/不太满意。接受调查的临床医生优先开具关节内透明质酸、口服非甾体抗炎药/对乙酰氨基酚、非药物干预和关节内皮质类固醇。临床医生选择的止痛治疗往往未能充分满足患者对缓解疼痛的期望。

结论

我们的研究结果突出了意大利KOA患者目前未满足的需求,并呼吁采用新方法来有效优化KOA相关疼痛的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/649e/11507079/5f3137f778f5/healthcare-12-02077-g001.jpg

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