文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

Clinical Applications of Micro/Nanobubble Technology in Neurological Diseases.

作者信息

Patel Parth B, Latt Sun, Ravi Karan, Razavi Mehdi

机构信息

University of Central Florida College of Medicine, Orlando, FL 32827, USA.

Biionix (Bionic Materials, Implants & Interfaces) Cluster, Department of Medicine, University of Central Florida College of Medicine, Orlando, FL 32827, USA.

出版信息

Biomimetics (Basel). 2024 Oct 20;9(10):645. doi: 10.3390/biomimetics9100645.

DOI:10.3390/biomimetics9100645
PMID:39451851
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11506587/
Abstract

Nanomedicine, leveraging the unique properties of nanoparticles, has revolutionized the diagnosis and treatment of neurological diseases. Among various nanotechnological advancements, ultrasound-mediated drug delivery using micro- and nanobubbles offers promising solutions to overcome the blood-brain barrier (BBB), enhancing the precision and efficacy of therapeutic interventions. This review explores the principles, current clinical applications, challenges, and future directions of ultrasound-mediated drug delivery systems in treating stroke, brain tumors, neurodegenerative diseases, and neuroinflammatory disorders. Additionally, ongoing clinical trials and potential advancements in this field are discussed, providing a comprehensive overview of the impact of nanomedicine on neurological diseases.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/52d7aa3c2d29/biomimetics-09-00645-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/259b1c6bc925/biomimetics-09-00645-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/935706429006/biomimetics-09-00645-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/1f6104831be8/biomimetics-09-00645-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/aba5a0db7155/biomimetics-09-00645-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/52d7aa3c2d29/biomimetics-09-00645-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/259b1c6bc925/biomimetics-09-00645-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/935706429006/biomimetics-09-00645-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/1f6104831be8/biomimetics-09-00645-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/aba5a0db7155/biomimetics-09-00645-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e7/11506587/52d7aa3c2d29/biomimetics-09-00645-g005.jpg

相似文献

[1]
Clinical Applications of Micro/Nanobubble Technology in Neurological Diseases.

Biomimetics (Basel). 2024-10-20

[2]
Mechanistic Insights and Therapeutic Delivery through Micro/Nanobubble-Assisted Ultrasound.

Pharmaceutics. 2022-2-22

[3]
Exploring chitosan nanoparticles for enhanced therapy in neurological disorders: a comprehensive review.

Naunyn Schmiedebergs Arch Pharmacol. 2025-3

[4]
Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases.

Adv Mater. 2018-7-31

[5]
Recent Advancements in Nanocarrier-assisted Brain Delivery of Phytochemicals Against Neurological Diseases.

Neurochem Res. 2023-10

[6]
Application of Therapeutic Nanoplatforms as a Potential Candidate for the Treatment of CNS Disorders: Challenges and Possibilities.

Curr Pharm Des. 2022

[7]
Nanotechnology-driven therapies for neurodegenerative diseases: a comprehensive review.

Ther Deliv. 2024

[8]
Nanoparticle-based Gene Therapy for Neurodegenerative Disorders.

Mini Rev Med Chem. 2024

[9]
Nanomedicine: A New Frontier in Alzheimer's Disease Drug Targeting.

Cent Nerv Syst Agents Med Chem. 2025

[10]
Blood-Brain Barrier-Targeting Nanoparticles: Biomaterial Properties and Biomedical Applications in Translational Neuroscience.

Pharmaceuticals (Basel). 2024-5-10

本文引用的文献

[1]
Removal of surface-attached micro- and nanobubbles by ultrasonic cavitation in microfluidics.

Ultrason Sonochem. 2024-10

[2]
Enhancing the bioavailability and activity of natural antioxidants with nanobubbles and nanoparticles.

Redox Rep. 2024-12

[3]
Sonothrombolysis for Ischemic Stroke.

J Cardiovasc Dev Dis. 2024-2-22

[4]
From concept to early clinical trials: 30 years of microbubble-based ultrasound-mediated drug delivery research.

Adv Drug Deliv Rev. 2024-3

[5]
Extracellular vesicles encapsulated with caspase-1 inhibitor ameliorate experimental autoimmune myasthenia gravis through targeting macrophages.

J Control Release. 2023-12

[6]
Ultrasound-Mediated Drug Delivery: Sonoporation Mechanisms, Biophysics, and Critical Factors.

BME Front. 2022-1-29

[7]
First-in-human prospective trial of sonobiopsy in high-grade glioma patients using neuronavigation-guided focused ultrasound.

NPJ Precis Oncol. 2023-9-16

[8]
High throughput microfluidic nanobubble generation by microporous membrane integration and controlled bubble shrinkage.

J Colloid Interface Sci. 2024-1

[9]
Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients.

Theranostics. 2023

[10]
Bubble-Based Drug Delivery Systems: Next-Generation Diagnosis to Therapy.

J Funct Biomater. 2023-7-17

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索