Vivan Lavínia, Dos Anjos Souza Vinícius Ribeiro, Seffrin Aldo, de Lira Claudio Andre Barbosa, Vancini Rodrigo Luiz, Weiss Katja, Knechtle Beat, Andrade Marilia Santos
Postgraduate Program in Translation Medicine, Federal University of São Paulo, São Paulo 04023-062, Brazil.
Human and Exercise Physiology Division, Faculty of Physical Education and Dance, Federal University of Goiás, Goiás 74690-900, Brazil.
Geriatrics (Basel). 2024 Oct 4;9(5):127. doi: 10.3390/geriatrics9050127.
BACKGROUND/OBJECTIVES: Sarcopenia is a muscular disease characterized by loss of muscular strength and function, affecting mainly women, and associated with increased mortality risk. The aim of this study was to compare active women with inactive women of different age groups regarding muscle mass, strength, and muscle quality.
This study included 147 women (85 runners and 62 inactive), divided into <50 and ≥50 years old. Participants were evaluated for knee flexor and extensor peak torque (PT), body composition, and training habits.
For knee extensor muscles, there was an age group effect (F(2.146) = 40.5; < 0.001) on absolute PT (Nm); an age group effect (F(2.146) = 44.1; < 0.001) and a physical activity group effect (F(2.146) = 113.0; < 0.001) on PT adjusted by body mass (Nm/kg); and an age group effect (F(2.146) = 36.9; < 0.001) and a physical activity group effect (F(2.146) = 6.1; = 0.014) on PT adjusted by lean mass (Nm/kgLM). There was no interaction effect.
In both age groups, active women had greater strength and higher muscle quality than inactive women, but the difference in strength, muscle mass, and muscle quality between younger and older women were the same among runners and inactive women.
背景/目的：肌肉减少症是一种以肌肉力量和功能丧失为特征的肌肉疾病，主要影响女性，并与死亡风险增加相关。本研究的目的是比较不同年龄组的活跃女性和不活跃女性在肌肉质量、力量和肌肉质量方面的差异。
本研究纳入了147名女性（85名跑步者和62名不活跃者），分为<50岁和≥50岁两组。对参与者进行了膝部屈伸肌峰值扭矩（PT）、身体成分和训练习惯的评估。
对于膝部伸肌，绝对PT（Nm）存在年龄组效应（F(2.146)=40.5；<0.001）；按体重调整后的PT（Nm/kg）存在年龄组效应（F(2.146)=44.1；<0.001）和身体活动组效应（F(2.146)=113.0；<0.001）；按瘦体重调整后的PT（Nm/kgLM）存在年龄组效应（F(2.146)=36.9；<0.001）和身体活动组效应（F(2.146)=6.1；=0.014）。不存在交互作用效应。
在两个年龄组中，活跃女性比不活跃女性具有更大的力量和更高的肌肉质量，但年轻女性和年长女性在力量、肌肉质量和肌肉质量方面的差异在跑步者和不活跃女性中是相同的。
