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棘手难题:一例罕见的子宫内膜异位症所致肠梗阻病例及文献综述

Twisted Troubles: A Rare Case of Intestinal Obstruction Due to Endometriosis and a Review of the Literature.

作者信息

Iordache Ionut Eduard, Alexandrescu Luana, Nicoara Alina Doina, Popescu Razvan, Leopa Nicoleta, Baltatescu Gabriela, Nelson Twakor Andreea, Tofolean Ionut Tiberiu, Steriu Liliana

机构信息

Department of General Surgery, "Sf. Apostol Andrei" Emergency County Hospital, 145 Tomis Blvd., 900591 Constanta, Romania.

Faculty of Medicine and Pharmacy Constanta, Ovidius University, 900470 Constanta, Romania.

出版信息

Clin Pract. 2024 Sep 27;14(5):2027-2043. doi: 10.3390/clinpract14050160.

Abstract

BACKGROUND AND OBJECTIVES

Intestinal endometriosis is an exceptionally rare cause of intestinal obstruction. This case report and literature review aim to highlight the clinical presentation, diagnostic challenges, and surgical management of this condition.

MATERIALS AND METHODS

We report the case of a 50-year-old female patient who presented diffuse abdominal pain, nausea, vomiting, a distended abdomen, and an absence of intestinal transit for gas and faeces. Initial symptoms included flatulence and constipation, which gradually worsened for two months prior to the patient's hospital admission, leading to acute intestinal obstruction. Diagnostic investigations, including blood tests, ultrasound (USG), X-ray, and a contrast-enhanced computer tomography (CT) scan, revealed significant small bowel dilatation and an ileal volvulus. The patient underwent urgent hydro-electrolytic and metabolic rebalancing followed by a median laparotomy surgical procedure. Intraoperative findings included a distended small intestine and an obstructive ileal volvulus, and required an 8 cm segmental enterectomy and terminal ileostomy.

RESULTS

Postoperative recovery was slow but favourable, with a gradual digestive tolerance. Histopathological examination of the resected ileum revealed intestinal endometriosis characterized by a fibro-conjunctive reaction and nonspecific chronic active inflammation. Five months later, the patient underwent a successful reversal of the ileostomy with a mechanical lateral anastomosis of the cecum and ileum, resulting in a favourable postoperative course.

CONCLUSIONS

This case underscores the importance of considering intestinal endometriosis in women presenting with unexplained gastrointestinal symptoms and highlights the need for timely surgical intervention and careful postoperative management. Further research is required to better understand the pathophysiology and optimal treatment strategies for intestinal endometriosis.

摘要

背景与目的

肠道子宫内膜异位症是肠梗阻极为罕见的病因。本病例报告及文献综述旨在突出该病症的临床表现、诊断挑战及手术治疗。

材料与方法

我们报告了一名50岁女性患者的病例,该患者出现弥漫性腹痛、恶心、呕吐、腹部膨隆,且无气体和粪便的肠道蠕动。初始症状包括肠胃胀气和便秘,在患者入院前两个月逐渐加重,导致急性肠梗阻。诊断性检查,包括血液检查、超声(USG)、X线及增强计算机断层扫描(CT),显示小肠显著扩张及回肠扭转。患者先接受了紧急水电解质及代谢平衡治疗,随后进行了正中剖腹手术。术中发现包括小肠扩张及梗阻性回肠扭转,需行8厘米节段性肠切除术及末端回肠造口术。

结果

术后恢复缓慢但情况良好,消化耐受性逐渐增强。切除回肠的组织病理学检查显示为肠道子宫内膜异位症,其特征为纤维结缔组织反应及非特异性慢性活动性炎症。五个月后,患者成功进行了回肠造口术逆转,行盲肠与回肠机械性侧侧吻合术,术后恢复良好。

结论

本病例强调了在出现不明原因胃肠道症状的女性中考虑肠道子宫内膜异位症的重要性,并突出了及时手术干预及术后精心管理的必要性。需要进一步研究以更好地理解肠道子宫内膜异位症的病理生理学及最佳治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3e5/11506226/3dd78f5d4c30/clinpract-14-00160-g001.jpg

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