Contrada Marianna, Scarfone Federica, Raso Maria Girolama, Lucca Lucia Francesca, Cerasa Antonio, Pugliese Maria Elena
Sant'Anna Institute, Via Siris 11, 88900 Crotone, Italy.
Institute of BioImaging and Complex Biological Systems (IBSBC-CNR), Via T. Campanella, 88100 Catanzaro, Italy.
Brain Sci. 2024 Oct 19;14(10):1038. doi: 10.3390/brainsci14101038.
BACKGROUND/OBJECTIVES: Cranioplasty (CP) is the main surgical procedure aiming to repair a morphological defect in the skull. It has been shown that early CP is useful for patients with traumatic brain injury (TBI) to achieve functional recovery, whereas few studies have investigated the clinical effects of ultra-late CP on TBI outcomes.
Here, we describe the clinical course over 2 years of a TBI patient who underwent CP 19 months after fronto-parietal decompressive craniectomy (DC) of a limited size.
We found that after ultra-late CP, a meaningful functional recovery (cognitive and motor), with emergence from a minimally conscious state and recovery of functional communication, was revealed.
Our preliminary findings contribute to the actual debate on the timing of CP for this neurosurgical procedure's therapeutic success, as early CP has already been shown.
背景/目的：颅骨修补术（CP）是旨在修复颅骨形态缺陷的主要外科手术。研究表明，早期颅骨修补术对创伤性脑损伤（TBI）患者实现功能恢复有益，而很少有研究探讨超晚期颅骨修补术对TBI预后的临床效果。
在此，我们描述了1例TBI患者在进行有限大小的额颞顶减压颅骨切除术（DC）19个月后接受颅骨修补术的2年临床过程。
我们发现，超晚期颅骨修补术后，患者出现了有意义的功能恢复（认知和运动），从最小意识状态苏醒，并恢复了功能性交流。
我们的初步研究结果为关于颅骨修补术时机对该神经外科手术治疗成功与否的实际辩论做出了贡献，正如早期颅骨修补术已被证明的那样。
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