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一名年轻男性的进展性胸腰椎结核:诊断、治疗及手术见解

Progressive Thoracolumbar Tuberculosis in a Young Male: Diagnostic, Therapeutic, and Surgical Insights.

作者信息

Nedelea Dana-Georgiana, Vulpe Diana Elena, Viscopoleanu George, Radulescu Alexandru Constantin, Mihailescu Alexandra Ana, Gradinaru Sebastian, Orghidan Mihnea, Scheau Cristian, Cergan Romica, Dragosloveanu Serban

机构信息

Department of Orthopaedics, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania.

Department of Anesthesiology and Critical Care, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania.

出版信息

Infect Dis Rep. 2024 Oct 12;16(5):1005-1016. doi: 10.3390/idr16050080.

Abstract

OBJECTIVE

We present the case of a 26-year-old male with severe spinal tuberculosis of the thoracolumbar region. The patient suffered from worsening back pain over five years, initially responding to over-the-counter analgesics. Despite being proposed surgery in 2019, the patient refused the intervention and subsequently experienced significant disease progression.

METHODS

Upon re-presentation in 2022, mild involvement of the T12-L1 vertebrae was recorded by imaging, leading to a percutaneous needle biopsy which confirmed tuberculosis. Despite undergoing anti-tuberculous therapy for one year, the follow-up in 2024 revealed extensive infection from T10 to S1, with large psoas abscesses and a pseudo-tumoral mass of the right thigh. The patient was ultimately submitted to a two-stage surgical intervention: anterior resection and reconstruction of T11-L1 with an expandable cage, followed by posterior stabilization from T8-S1.

RESULTS

Postoperative recovery was uneventful, with significant pain relief and no neurological deficits. The patient was discharged on a continued anti-tuberculous regimen and remains under close surveillance.

CONCLUSIONS

This paper presents details on the challenges of diagnosis and management of severe spinal tuberculosis, with emphasis on the importance of timely intervention and multidisciplinary care.

摘要

目的

我们报告一例26岁胸腰段严重脊柱结核男性病例。该患者五年多来背痛逐渐加重,最初服用非处方镇痛药有效。尽管在2019年建议其手术,但患者拒绝干预,随后病情显著进展。

方法

2022年再次就诊时,影像学检查显示T12-L1椎体轻度受累,遂进行经皮穿刺活检,确诊为结核病。尽管接受了一年的抗结核治疗,但2024年的随访显示,感染范围从T10扩展至S1,伴有巨大的腰大肌脓肿和右侧大腿的假瘤样肿块。患者最终接受了两阶段手术干预:采用可扩张椎间融合器对T11-L1进行前路切除和重建,随后从T8-S1进行后路固定。

结果

术后恢复顺利,疼痛明显缓解,无神经功能缺损。患者出院时继续接受抗结核治疗,仍在密切监测中。

结论

本文详细介绍了严重脊柱结核诊断和治疗的挑战,强调了及时干预和多学科护理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7f4/11507176/1152b160801c/idr-16-00080-g001.jpg

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