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普通X线摄影在日常实践中评估流产胎儿肌肉骨骼异常的作用。

The Role of Plain Radiography in Assessing Aborted Foetal Musculoskeletal Anomalies in Everyday Practice.

作者信息

Rossini Benedetta, Carnevale Aldo, Parenti Gian Carlo, Zago Silvia, Sigolo Guendalina, Feletti Francesco

机构信息

Unit of Radiology, S. Maria delle Croci Hospital, Ausl Romagna, 48121 Ravenna, Italy.

Dipartimento di Medicina Traslazionale e per la Romagna, Università degli Studi di Ferrara, 44121 Ferrara, Italy.

出版信息

J Imaging. 2024 Sep 27;10(10):242. doi: 10.3390/jimaging10100242.

Abstract

Conventional radiography is widely used for postmortem foetal imaging, but its role in diagnosing congenital anomalies is debated. This study aimed to assess the effectiveness of X-rays in detecting skeletal abnormalities and guiding genetic analysis and counselling. This is a retrospective analysis of all post-abortion diagnostic imaging studies conducted at a centre serving a population of over 300,000 inhabitants from 2008 to 2023. The data were analysed using descriptive statistics. X-rays of 81 aborted foetuses (total of 308 projections; mean: 3.8 projections/examination; SD: 1.79) were included. We detected 137 skeletal anomalies. In seven cases (12.7%), skeletal anomalies identified through radiology were missed by prenatal sonography. The autopsy confirmed radiological data in all cases except for two radiological false positives. Additionally, radiology failed to identify a case of syndactyly, which was revealed by anatomopathology. X-ray is crucial for accurately classifying skeletal abnormalities, determining the causes of spontaneous abortion, and guiding the request for genetic counselling. Formal training for both technicians and radiologists, as well as multidisciplinary teamwork, is necessary to perform X-ray examinations on aborted foetuses and interpret the results effectively.

摘要

传统放射成像广泛用于死产胎儿成像,但其在诊断先天性异常中的作用存在争议。本研究旨在评估X射线在检测骨骼异常以及指导基因分析和咨询方面的有效性。这是一项对2008年至2023年在一个为超过30万居民服务的中心进行的所有流产后诊断成像研究的回顾性分析。数据采用描述性统计进行分析。纳入了81例流产胎儿的X射线检查(共308个投照;平均:3.8个投照/检查;标准差:1.79)。我们检测到137例骨骼异常。在7例(12.7%)中,产前超声检查漏诊了通过放射学检查发现的骨骼异常。除了2例假阳性放射学结果外,尸检证实了所有病例的放射学数据。此外,放射学检查未能识别出1例并指畸形,该病例由解剖病理学检查发现。X射线对于准确分类骨骼异常、确定自然流产原因以及指导基因咨询申请至关重要。对技术人员和放射科医生进行正规培训以及开展多学科团队合作,对于对流产胎儿进行X射线检查并有效解读结果而言是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67a1/11508908/a74e2a143cb8/jimaging-10-00242-g001.jpg

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