IPREM-Institute of Analytical Sciences and Physico-Chemistry for Environment and Materials, Universite de Pau et des Pays de l'Adour, E2S UPPA, CNRS, 64000 Pau, France.
Mar Drugs. 2024 Oct 16;22(10):473. doi: 10.3390/md22100473.
In the past few years, there has been an increasing interest in mycosporines-UV-absorbing molecules-bringing important insights into their intrinsic properties as natural sunscreens. Herein, mycosporine-serinol and gadusol (enolate form)/gadusolate were exposed to UV radiation via a solar simulator and the photostability was assessed in pure water and different natural matrices like river, estuary and ocean water. In general, this study revealed that the photodegradation of gadusolate and mycosporine-serinol was higher in natural matrices than in pure water due to the generation of singlet oxygen on UV irradiation. In pure water, in terms of photostability, both gadusolate and mycosporine-serinol were found to offer good protection and high performance in terms of photodegradation quantum yield ((0.8 ± 0.2) × 10 and (1.1 ± 0.6) × 10, respectively). Nonetheless, the photostability of mycosporine-serinol was found to be superior to that of gadusolate in natural water, namely, ocean, estuary and river. The present work highlights how mycosporine-serinol and gadusolate resist photodegradation, and supports their role as effective and stable UV-B sunscreens.
在过去的几年中，人们对具有吸收紫外线功能的微生物菌 醇类化合物（mycosporines-UV-absorbing molecules）越来越感兴趣，这为人们深入了解其作为天然防晒霜的固有特性提供了重要线索。本研究通过太阳模拟器对微生物菌 醇和（烯醇式形式的）角鲨烯/角鲨烷（gadusol/gadusolate）进行了紫外线辐射，在纯水和不同的天然基质（如河流、河口和海水）中评估了其光稳定性。一般来说，由于紫外线照射下产生单线态氧，角鲨烷和微生物菌 醇在天然基质中的光降解率高于纯水。在纯水中，就光稳定性而言，角鲨烷和微生物菌 醇均表现出良好的保护作用，其光降解量子产率分别高达（0.8±0.2）×10 和（1.1±0.6）×10。然而，在天然水中，如海洋、河口和河流中，微生物菌 醇的光稳定性优于角鲨烷。本研究强调了微生物菌 醇和角鲨烷如何抵抗光降解，并支持它们作为有效和稳定的 UV-B 防晒霜的作用。
