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使用超声衰减成像(ATI)评估高脂血症犬的肝实质

Evaluation of Liver Parenchyma in Dogs with Hyperlipidemia Using Ultrasound Attenuation Imaging (ATI).

作者信息

Pelligra Tina, Citi Simonetta, Marchetti Veronica, Habermaass Verena, Tinalli Sara, Puccinelli Caterina

机构信息

Department of Veterinary Sciences, University of Pisa, Via Livornese Lato Monte, San Piero a Grado, 56122 Pisa, Italy.

出版信息

Vet Sci. 2024 Sep 25;11(10):454. doi: 10.3390/vetsci11100454.

Abstract

(1) Background: Ultrasound attenuation imaging (ATI) is an innovative technique that allows for the evaluation of the degree of lipid infiltration of the liver parenchyma in a simple and non-invasive way. The objective of this study was to verify the applicability of the ATI method in the evaluation of hyperlipidemia. (2) Methods: This study included 53 dogs between January 2021 and December 2022, of which 21 were healthy (A) and 32 had hyperlipidemia (B). The dogs of Group B were divided into mild hyperlipidemic (B1; n = 15) and moderate/severe hyperlipidemic (B2; n = 17). Each dog underwent biochemical examination, B-mode ultrasound and ATI investigation at the liver level via a right intercostal approach. (3) Results: The mean AC value was significantly higher in Group B (0.95 ± 0.23 dB/cm/MHz) compared to Group A (0.81 ± 0.10 dB/cm/MHz). No statistically significant differences were highlighted regarding the ATI values between the subjects with mild and moderate/severe hyperlipidemia. (4) Conclusion: ATI could be a promising method for the non-invasive evaluation of hepatic steatosis in veterinary medicine.

摘要

(1) 背景:超声衰减成像(ATI)是一种创新技术,能够以简单且无创的方式评估肝实质的脂质浸润程度。本研究的目的是验证ATI方法在高脂血症评估中的适用性。(2) 方法:本研究纳入了2021年1月至2022年12月期间的53只犬,其中21只为健康犬(A组),32只患有高脂血症(B组)。B组犬又分为轻度高脂血症组(B1组;n = 15)和中度/重度高脂血症组(B2组;n = 17)。每只犬均接受了生化检查、B超检查以及通过右肋间途径对肝脏进行的ATI检查。(3) 结果:与A组(0.81 ± 0.10 dB/cm/MHz)相比,B组的平均AC值显著更高(0.95 ± 0.23 dB/cm/MHz)。轻度与中度/重度高脂血症患者之间的ATI值未发现有统计学意义的差异。(4) 结论:在兽医学中,ATI可能是一种用于非侵入性评估肝脂肪变性的有前景的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92e9/11512394/04011cf61a69/vetsci-11-00454-g001.jpg

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