日本家养和流浪猫中猫传染性肠炎冠状病毒无症状感染的分子流行病学和风险分析。
Molecular epidemiology and risk analysis for asymptomatic infection with feline enteric coronavirus in domestic and stray cats in Japan.
机构信息
Laboratory of Veterinary Microbiology, Joint Department of Veterinary Medicine, Gifu University, Yanagido, Gifu, 501-1193, Japan.
Joint Graduate School of Veterinary Sciences, Gifu University, Yanagido, Gifu, 501-1193, Japan.
出版信息
Arch Virol. 2024 Oct 25;169(11):230. doi: 10.1007/s00705-024-06164-7.
Feline enteric coronavirus (FECoV) causes subclinical infection; therefore, asymptomatic cats can act as transmitters of FECoV. However, there have been few studies on the prevalence of FECoV in asymptomatic cats in Japan. In this study, we used a nested RT-PCR assay targeting the S gene of FECoV to test 319 normal fecal samples from stray cats and domestic cats in Japan between 2019 and 2020. Seventy-five samples tested positive, and the presence of FECoV in domestic cats was significantly associated with age (p < 0.01), but not with gender, breed, or living in a multi-cat household. The results provide insights into the current prevalence of FECoV in asymptomatic cats in Japan.
猫肠道冠状病毒（FECoV）引起亚临床感染；因此，无症状的猫可能成为 FECoV 的传播者。然而，在日本，关于无症状猫中 FECoV 的流行率的研究较少。在这项研究中，我们使用针对 FECoV S 基因的巢式 RT-PCR 检测法，检测了 2019 年至 2020 年间日本的 319 份流浪猫和家猫的正常粪便样本。75 个样本呈阳性，FECoV 在家猫中的存在与年龄显著相关（p<0.01），但与性别、品种或生活在多猫家庭无关。结果为了解日本无症状猫中 FECoV 的当前流行率提供了线索。
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