Laboratory of Veterinary Microbiology, Joint Department of Veterinary Medicine, Gifu University, Yanagido, Gifu, 501-1193, Japan.
Joint Graduate School of Veterinary Sciences, Gifu University, Yanagido, Gifu, 501-1193, Japan.
Arch Virol. 2024 Oct 25;169(11):230. doi: 10.1007/s00705-024-06164-7.
Feline enteric coronavirus (FECoV) causes subclinical infection; therefore, asymptomatic cats can act as transmitters of FECoV. However, there have been few studies on the prevalence of FECoV in asymptomatic cats in Japan. In this study, we used a nested RT-PCR assay targeting the S gene of FECoV to test 319 normal fecal samples from stray cats and domestic cats in Japan between 2019 and 2020. Seventy-five samples tested positive, and the presence of FECoV in domestic cats was significantly associated with age (p < 0.01), but not with gender, breed, or living in a multi-cat household. The results provide insights into the current prevalence of FECoV in asymptomatic cats in Japan.
猫肠道冠状病毒（FECoV）引起亚临床感染；因此，无症状的猫可能成为 FECoV 的传播者。然而，在日本，关于无症状猫中 FECoV 的流行率的研究较少。在这项研究中，我们使用针对 FECoV S 基因的巢式 RT-PCR 检测法，检测了 2019 年至 2020 年间日本的 319 份流浪猫和家猫的正常粪便样本。75 个样本呈阳性，FECoV 在家猫中的存在与年龄显著相关（p<0.01），但与性别、品种或生活在多猫家庭无关。结果为了解日本无症状猫中 FECoV 的当前流行率提供了线索。
