Brooke M H, Choksi R, Kaiser K K
Neurology. 1986 Feb;36(2):288-91. doi: 10.1212/wnl.36.2.288.
An in vitro system of muscle stimulation has been developed that combines physiologic measurements with biochemical evaluation. In the rat epitrochlearis muscle, 2 minutes of stimulation at 4 Hz results in a marked elevation of inosine monophosphate (IMP) levels. The amount of IMP generated is proportional to the amount of force developed. Depriving the muscle of oxygen results in an increased amount of IMP generation. This model provides direct confirmation of similar findings in the human forearm exercise test.
已开发出一种肌肉刺激体外系统，该系统将生理测量与生化评估相结合。在大鼠肱三头肌中，以4Hz频率刺激2分钟会导致肌苷单磷酸（IMP）水平显著升高。产生的IMP量与所产生的力量大小成正比。剥夺肌肉的氧气会导致IMP生成量增加。该模型直接证实了人体前臂运动试验中的类似发现。
