Alsayed Hawra Ali Hussain, Saheb Sharif-Askari Narjes, Saheb Sharif-Askari Fatemeh, Halwani Rabih
Department of Pharmacy, Rashid Hospital, Dubai Academic Health Corporation, Dubai, United Arab Emirates; Research Institute for Medical and Health Science, University of Sharjah, Sharjah, United Arab Emirates.
Research Institute for Medical and Health Science, University of Sharjah, Sharjah, United Arab Emirates; Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.
Am J Infect Control. 2025 Mar;53(3):326-329. doi: 10.1016/j.ajic.2024.10.016. Epub 2024 Oct 23.
Elizabethkingia meningoseptica (E. meningoseptica) is a gram-negative bacillus. Widely distributed in nature, it poses a significant threat as a nosocomial pathogen, particularly affecting immunocompromised neonates and the elderly.
This study aimed to describe the antimicrobial susceptibility and outcomes of E. meningoseptica infections over seven years in United Arab Emirates. A retrospective chart review study was conducted at four hospitals that are part of Dubai Academic Health Corporation.
A total of 23 cases were observed during the study, 21 (91%) of which exhibited multidrug resistance. More than half of the cases required intensive care and mechanical ventilation (n = 13, 57%). The in-hospital mortality rate was 38% (n = 5) in adults and 20% (n = 2) in pediatrics.
E. meningoseptica is a significant nosocomial pathogen with high antibiotic resistance, posing severe risks to immunocompromised pediatric and adult patients. Effective management of E. meningoseptica requires vigilant monitoring, comprehensive control, and targeted therapies.
脑膜败血伊丽莎白金菌（E. meningoseptica）是一种革兰氏阴性杆菌。它广泛分布于自然界，作为一种医院病原体构成重大威胁，尤其影响免疫功能低下的新生儿和老年人。
本研究旨在描述阿拉伯联合酋长国七年间脑膜败血伊丽莎白金菌感染的抗菌药物敏感性及转归情况。在迪拜学术健康集团下属的四家医院开展了一项回顾性病历审查研究。
研究期间共观察到23例病例，其中21例（91%）表现出多重耐药性。超过半数的病例需要重症监护和机械通气（n = 13，57%）。成人的院内死亡率为38%（n = 5），儿科患者为20%（n = 2）。
脑膜败血伊丽莎白金菌是一种具有高耐药性的重要医院病原体，对免疫功能低下的儿科和成人患者构成严重风险。有效管理脑膜败血伊丽莎白金菌需要进行密切监测、全面控制和针对性治疗。
