Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th Street .450N, Miami, FL, 33136, USA.
Sci Rep. 2024 Oct 25;14(1):25300. doi: 10.1038/s41598-024-76352-7.
We conducted a retrospective review of patients (< 18 years) between 2013 and 2021 to determine risk factors of pediatric patients receiving a glaucoma drainage device (GDD) needing a scleral buckle (SB) and vice versa. The first population underwent an SB placement with no prior GDD. The second underwent a GDD implantation with no prior SB. We analyzed 133 eyes in the SB-first group. The common indications were retinal detachment associated with a syndrome/disease (41.2%), blunt trauma (21%), and non-syndromic pathologic myopia (11%). Twelve eyes (9%) required subsequent GDD implantation with a mean time to reoperation of 19.73 months (median 2.3 months). Eyes with trauma had a 5-fold risk (hazard ratio [HR] 4.81, p = 0.0069) of requiring a subsequent GDD. Each additional glaucoma medication before initial SB surgery increased the risk by 1.81 (p = 0.0096). 135 eyes were in the GDD-first group. Four eyes (3%) required a subsequent SB. The mean time to reoperation was 17 months (median 9.2 months). There was a statistically significant association with trauma (HR 12.3, p = 0.0341) only. Pediatric eyes with a history of trauma and/or multiple glaucoma medications before intervention have a high risk of requiring both an SB and GDD.
我们回顾性分析了 2013 年至 2021 年间接受青光眼引流装置(GDD)和巩膜扣带术(SB)治疗的儿童患者的风险因素。第一组患者首次接受 SB 治疗,之前未接受 GDD 治疗。第二组患者首次接受 GDD 植入术,之前未接受 SB 治疗。我们分析了 SB 组的 133 只眼。常见的适应证为伴有综合征/疾病的视网膜脱离(41.2%)、钝挫伤(21%)和非综合征性病理性近视(11%)。12 只眼(9%)需要随后植入 GDD,再次手术的平均时间为 19.73 个月(中位数 2.3 个月)。有创伤的眼再次植入 GDD 的风险增加 5 倍(风险比 [HR] 4.81,p = 0.0069)。初次 SB 手术前每增加一种额外的青光眼药物,风险增加 1.81(p = 0.0096)。GDD 组有 135 只眼。4 只眼(3%)需要随后接受 SB 治疗。再次手术的平均时间为 17 个月(中位数 9.2 个月)。仅与创伤有统计学显著相关性(HR 12.3,p = 0.0341)。有创伤史和/或干预前有多种青光眼药物史的儿科患者同时需要 SB 和 GDD 的风险较高。