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儿童同时接受巩膜扣带术和青光眼引流装置的风险因素。

Risk factors for receiving both scleral buckle and glaucoma drainage device in children.

机构信息

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th Street .450N, Miami, FL, 33136, USA.

出版信息

Sci Rep. 2024 Oct 25;14(1):25300. doi: 10.1038/s41598-024-76352-7.

Abstract

We conducted a retrospective review of patients (< 18 years) between 2013 and 2021 to determine risk factors of pediatric patients receiving a glaucoma drainage device (GDD) needing a scleral buckle (SB) and vice versa. The first population underwent an SB placement with no prior GDD. The second underwent a GDD implantation with no prior SB. We analyzed 133 eyes in the SB-first group. The common indications were retinal detachment associated with a syndrome/disease (41.2%), blunt trauma (21%), and non-syndromic pathologic myopia (11%). Twelve eyes (9%) required subsequent GDD implantation with a mean time to reoperation of 19.73 months (median 2.3 months). Eyes with trauma had a 5-fold risk (hazard ratio [HR] 4.81, p = 0.0069) of requiring a subsequent GDD. Each additional glaucoma medication before initial SB surgery increased the risk by 1.81 (p = 0.0096). 135 eyes were in the GDD-first group. Four eyes (3%) required a subsequent SB. The mean time to reoperation was 17 months (median 9.2 months). There was a statistically significant association with trauma (HR 12.3, p = 0.0341) only. Pediatric eyes with a history of trauma and/or multiple glaucoma medications before intervention have a high risk of requiring both an SB and GDD.

摘要

我们回顾性分析了 2013 年至 2021 年间接受青光眼引流装置(GDD)和巩膜扣带术(SB)治疗的儿童患者的风险因素。第一组患者首次接受 SB 治疗,之前未接受 GDD 治疗。第二组患者首次接受 GDD 植入术,之前未接受 SB 治疗。我们分析了 SB 组的 133 只眼。常见的适应证为伴有综合征/疾病的视网膜脱离(41.2%)、钝挫伤(21%)和非综合征性病理性近视(11%)。12 只眼(9%)需要随后植入 GDD,再次手术的平均时间为 19.73 个月(中位数 2.3 个月)。有创伤的眼再次植入 GDD 的风险增加 5 倍(风险比 [HR] 4.81,p = 0.0069)。初次 SB 手术前每增加一种额外的青光眼药物,风险增加 1.81(p = 0.0096)。GDD 组有 135 只眼。4 只眼(3%)需要随后接受 SB 治疗。再次手术的平均时间为 17 个月(中位数 9.2 个月)。仅与创伤有统计学显著相关性(HR 12.3,p = 0.0341)。有创伤史和/或干预前有多种青光眼药物史的儿科患者同时需要 SB 和 GDD 的风险较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47f0/11511900/fb81ac9ed737/41598_2024_76352_Fig1_HTML.jpg

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