Huang Y S, Cunnane S C, Horrobin D F
Proc Soc Exp Biol Med. 1986 Mar;181(3):399-403. doi: 10.3181/00379727-181-42271.
Weanling male rats were fed semipurified diets containing 20% protein derived from casein, soy protein, or wheat gluten for 5 weeks. The fat source was 2% safflower oil (containing 79.4% 18:2n-6). In comparison with the casein-fed rats, the growth rate of rats fed plant proteins was slower, particularly that of rats fed the wheat gluten diet. The plasma cholesterol levels were significantly lower in rats fed wheat gluten than in those fed the other dietary protein regimens. The fatty acid compositions of plasma and liver lipids were also examined. The ratios of 16:1/16:0, 18:1/18:0 and 20:4n-6/18:2n-6 in both plasma and liver phospholipids and cholesteryl esters were consistently reduced in animals fed plant protein suggesting a reduced activity of fatty acid desaturation. The reduction of fatty acid desaturation may possibly be attributed to the low lysine/arginine ratio in plant proteins.
将断乳雄性大鼠用含20%源自酪蛋白、大豆蛋白或小麦面筋的蛋白质的半纯化日粮喂养5周。脂肪来源为2%的红花油（含79.4%的18:2n-6）。与喂食酪蛋白的大鼠相比，喂食植物蛋白的大鼠生长速度较慢，尤其是喂食小麦面筋日粮的大鼠。喂食小麦面筋的大鼠血浆胆固醇水平显著低于喂食其他日粮蛋白质方案的大鼠。还检测了血浆和肝脏脂质的脂肪酸组成。在喂食植物蛋白的动物中，血浆和肝脏磷脂及胆固醇酯中的16:1/16:0、18:1/18:0和20:4n-6/18:2n-6的比例持续降低，表明脂肪酸去饱和活性降低。脂肪酸去饱和的降低可能归因于植物蛋白中赖氨酸/精氨酸比例较低。
