无所不在且多面的辅酶Q
The Ubiquitous and Multifaceted Coenzyme Q.
作者信息
Tiano Luca, Navas Plácido
机构信息
Department of Life and Environmental Sciences (DISVA), Marche Polytechnic University, 60131 Ancona, Italy.
Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC-JA, 41013 Sevilla, Spain.
出版信息
Antioxidants (Basel). 2024 Oct 17;13(10):1261. doi: 10.3390/antiox13101261.
Abstract
Coenzyme Q (CoQ) is composed of a benzoquinone ring and an isoprenoid side chain attached to carbon 3 of the ring [...].
摘要
辅酶Q（CoQ）由一个苯醌环和一个连接在环上第3位碳原子的类异戊二烯侧链组成[……]。
相似文献
1
The Ubiquitous and Multifaceted Coenzyme Q.无所不在且多面的辅酶Q
Antioxidants (Basel). 2024 Oct 17;13(10):1261. doi: 10.3390/antiox13101261.
2
Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum.恶性疟原虫中辅酶Q类异戊二烯链的特性研究
FEMS Microbiol Lett. 2002 Jan 22;207(1):13-20. doi: 10.1111/j.1574-6968.2002.tb11021.x.
3
The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus.辅酶Q-10在衰老、神经退行性变、心血管疾病、癌症和糖尿病中的新作用。
Curr Neurovasc Res. 2005 Dec;2(5):447-59. doi: 10.2174/156720205774962656.
4
Enhanced production techniques, properties and uses of coenzyme Q10.辅酶Q10的强化生产技术、性质及用途。
Biotechnol Lett. 2014 Oct;36(10):1917-26. doi: 10.1007/s10529-014-1587-1. Epub 2014 Jul 22.
5
Bioavailability enhancement of coenzyme Q: An update of novel approaches.辅酶 Q 生物利用度的增强：新方法的更新。
Arch Pharm (Weinheim). 2024 Aug;357(8):e2300676. doi: 10.1002/ardp.202300676. Epub 2024 Apr 29.
6
A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport, and antioxidant function in Saccharomyces cerevisiae.在酿酒酵母中，高效的辅酶Q生物合成、呼吸电子传递和抗氧化功能需要一种保守的START结构域辅酶Q结合多肽。
Biochim Biophys Acta. 2013 Apr;1831(4):776-791. doi: 10.1016/j.bbalip.2012.12.007. Epub 2012 Dec 25.
7
CoQ10 a super-vitamin: review on application and biosynthesis.辅酶Q10——一种超级维生素：应用与生物合成综述
3 Biotech. 2018 May;8(5):249. doi: 10.1007/s13205-018-1271-6. Epub 2018 May 9.
8
Metabolism of coenzyme Q10: biliary and urinary excretion study in guinea pigs.辅酶Q10的代谢：豚鼠的胆汁和尿液排泄研究。
Biofactors. 1999;9(2-4):111-9. doi: 10.1002/biof.5520090205.
9
Cellular factories for coenzyme Q production.用于辅酶Q生产的细胞工厂。
Microb Cell Fact. 2017 Mar 2;16(1):39. doi: 10.1186/s12934-017-0646-4.
10
Characterization of Inclusion Complex of Coenzyme Q10 with the New Carrier CD-MOF-1 Prepared by Solvent Evaporation.溶剂挥发法制备新型载体 CD-MOF-1 包合辅酶 Q10 的特性研究。
AAPS PharmSciTech. 2018 Oct;19(7):3048-3056. doi: 10.1208/s12249-018-1136-7. Epub 2018 Aug 7.
引用本文的文献
1
Evaluating the Role of Coenzyme Q10 in Migraine Therapy-A Narrative Review.评估辅酶Q10在偏头痛治疗中的作用——一篇叙述性综述
Antioxidants (Basel). 2025 Mar 6;14(3):318. doi: 10.3390/antiox14030318.
本文引用的文献
1
Prenatal and progressive coenzyme Q administration to mitigate muscle dysfunction in mitochondrial disease.产前及逐步给予辅酶Q以减轻线粒体疾病中的肌肉功能障碍。
J Cachexia Sarcopenia Muscle. 2024 Dec;15(6):2402-2416. doi: 10.1002/jcsm.13574. Epub 2024 Oct 2.
2
Cancer cell stiffening via CoQ and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer.辅酶 Q 和 UBIAD1 使癌细胞变硬，调节乳腺癌中的细胞外基质信号和铁死亡。
Nat Commun. 2024 Sep 18;15(1):8214. doi: 10.1038/s41467-024-52523-y.
3
Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.补充大剂量辅酶 Q10 六个月可改善代谢功能障碍相关脂肪性肝病患者的肝脂肪变性、内皮、血管和心肌功能：一项随机、双盲、安慰剂对照试验。
Cardiovasc Diabetol. 2024 Jul 10;23(1):245. doi: 10.1186/s12933-024-02326-8.
4
Selenoprotein P increases upon selenium and coenzyme Q supplementation and is associated with telomere length, quality of life and reduced inflammation and mortality.补充硒和辅酶 Q 会增加硒蛋白 P 的含量，与端粒长度、生活质量以及减少炎症和降低死亡率相关。
Free Radic Biol Med. 2024 Sep;222:403-413. doi: 10.1016/j.freeradbiomed.2024.06.027. Epub 2024 Jul 2.
5
Ferroptosis in health and disease.铁死亡在健康和疾病中的作用。
Redox Biol. 2024 Sep;75:103211. doi: 10.1016/j.redox.2024.103211. Epub 2024 May 30.
6
Structural Reconstruction of Ubi Metabolon Using an AlphaFold2-Based Computational Framework.利用基于 AlphaFold2 的计算框架进行泛素代谢物的结构重建。
J Chem Inf Model. 2024 Jul 8;64(13):5175-5193. doi: 10.1021/acs.jcim.4c00304. Epub 2024 May 6.
7
4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.4- 羟基苯甲酸可挽救线粒体疾病小鼠模型中的多系统疾病和围产期致死性。
Cell Rep. 2024 May 28;43(5):114148. doi: 10.1016/j.celrep.2024.114148. Epub 2024 May 1.
8
Human embryonic genetic mosaicism and its effects on development and disease.人类胚胎基因嵌合现象及其对发育和疾病的影响。
Nat Rev Genet. 2024 Oct;25(10):698-714. doi: 10.1038/s41576-024-00715-z. Epub 2024 Apr 11.
9
In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis.辅酶Q代谢体的体外构建揭示了辅酶Q生物合成的分子决定因素。
Nat Catal. 2024 Jan 3;7(2):148-160. doi: 10.1038/s41929-023-01087-z.
10
The cell biology of ferroptosis.铁死亡的细胞生物学。
Nat Rev Mol Cell Biol. 2024 Jun;25(6):424-442. doi: 10.1038/s41580-024-00703-5. Epub 2024 Feb 16.
Zotero 插件