Department of Pathogenobiology, Key Laboratory of Pathobiology, Ministry of Education, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Int J Mol Sci. 2024 Oct 13;25(20):11016. doi: 10.3390/ijms252011016.
is a macrofungus that is used in traditional Chinese medicine for its insecticidal and stagnation-relieving properties. The active ingredients of this fungus including proteins, polysaccharides and sterols have been demonstrated to exhibit antiparasitic, anti-inflammatory, and antitumor effects. has been used in clinical cancer treatment. Many studies on have concentrated on its cytotoxicity and anticancer effects. However, the investigation of its natural metabolites remains a significant area for further research. This review presents a comprehensive analysis of the research progress concerning the pharmacological components of . The aim of this discussion is to provide a reference for further in-depth study of , with the objective of exploring its potential value. Therefore, the focus of this review was on the classification of metabolites in and their mechanisms of action.
灵芝是一种大型真菌,在中国传统医学中被用作杀虫剂和解郁药。该真菌的活性成分包括蛋白质、多糖和固醇,已被证明具有抗寄生虫、抗炎和抗肿瘤作用。灵芝已被用于临床癌症治疗。许多关于灵芝的研究集中在其细胞毒性和抗癌作用上。然而,对其天然代谢物的研究仍是一个有待进一步研究的重要领域。本综述全面分析了灵芝药理成分的研究进展。讨论的目的是为进一步深入研究灵芝提供参考,旨在探索其潜在价值。因此,本综述的重点是灵芝代谢产物的分类及其作用机制。