Samara Athina A, Diamantis Alexandros, Magouliotis Dimitrios, Tolia Maria, Tsavalas Vasileios, Tzovaras George, Tepetes Konstantinos
Department of Surgery, University Hospital of Larissa, 41110 Larissa, Greece.
Department of Radiotherapy, University of Crete, 73100 Chania, Greece.
J Clin Med. 2024 Oct 17;13(20):6193. doi: 10.3390/jcm13206193.
: In the present study, we aimed to investigate the association between (EORTC) QLQ-C30 scores and both preoperative somatometric parameters and postoperative outcomes in elderly patients undergoing elective surgery for resectable colorectal cancer. : The 118 elderly consecutive patients who underwent colorectal surgery for cancer in a single university's surgical department between 01/2018 and 12/2018 were prospectively enrolled in the present study. All patients with an age > 65 years, diagnosed with resectable colorectal cancer, without metastatic disease, that underwent elective surgery were included prospectively in the present study. : Regarding patients' characteristics, a negative correlation between preoperative QLQ (pQLQ) score and age ( = 0.001) and a positive correlation between body mass index (BMI) and pQLQ score ( = 0.048) were observed. Furthermore, there was a statistically significant difference ( = 0.004) in the mean pQLQ score between patients with rectal or colon cancer. Moreover, assessing pQLQ score was a useful tool in terms of postoperative recovery. Negative correlations between the pQLQ score and time (days) of beginning oral feeding ( < 0.001) and length of hospital stay ( = 0.004) were found. The pQLQ score was statistically significantly lower ( = 0.005) in patients who had any postoperative complication; however, there was no difference in patients with major complications. : Advanced age, colon cancer and decreased BMI were negatively associated with preoperative QLQ. The assessment of pQLQ in elderly patients with colorectal cancer can be a useful predictive tool for postoperative complications, length of hospital stay and postoperative rehabilitation.
在本研究中，我们旨在调查接受可切除结直肠癌择期手术的老年患者中，欧洲癌症研究与治疗组织（EORTC）QLQ-C30评分与术前身体测量参数及术后结果之间的关联。2018年1月至2018年12月期间，在一所大学外科接受结直肠癌手术的118例连续老年患者被前瞻性纳入本研究。所有年龄>65岁、诊断为可切除结直肠癌、无转移性疾病且接受择期手术的患者均被前瞻性纳入本研究。关于患者特征，观察到术前QLQ（pQLQ）评分与年龄呈负相关（r = 0.001），体重指数（BMI）与pQLQ评分呈正相关（r = 0.048）。此外，直肠癌或结肠癌患者的平均pQLQ评分存在统计学显著差异（r = 0.004）。此外，评估pQLQ评分是术后恢复方面的一个有用工具。发现pQLQ评分与开始经口进食的时间（天）（P<0.001）和住院时间（r = 0.004）呈负相关。发生任何术后并发症的患者的pQLQ评分在统计学上显著更低（P = 0.005）；然而，主要并发症患者之间没有差异。高龄、结肠癌和BMI降低与术前QLQ呈负相关。对老年结直肠癌患者的pQLQ评估可作为术后并发症、住院时间和术后康复的有用预测工具。
