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机器人辅助肺叶切除术后第二天早期出院及远程医疗家庭监测

Early Hospital Discharge on Day Two Post-Robotic Lobectomy with Telehealth Home Monitoring.

作者信息

Mangiameli Giuseppe, Bottoni Edoardo, Tagliabue Alberto, Giudici Veronica Maria, Crepaldi Alessandro, Testori Alberto, Voulaz Emanuele, Cariboni Umberto, Re Cecconi Emanuela, Luppichini Matilde, Alloisio Marco, Brascia Debora, Morenghi Emanuela, Marulli Giuseppe

机构信息

Division of Thoracic Surgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy.

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090 Milan, Italy.

出版信息

J Clin Med. 2024 Oct 21;13(20):6268. doi: 10.3390/jcm13206268.

Abstract

Despite the implementation of enhanced recovery programs, the reported average postoperative length of stay after robotic lobectomy remains as 4 days. In this prospective study, we present the outcomes of early discharge (on day 2) with telehealth home monitoring device after robotic lobectomy for lung cancer in selected patients. All patients with a caregiver were discharged on postoperative day 2 (POD 2) with a telemonitoring device provided they met the specific discharge criteria. Inclusion criteria: <75 years old, stage I-II NSCLC, with caregiver, ECOG 0-2, scheduled for lobectomy, logistic proximity to hospital (<60 km); intra-postoperative exclusion criteria: conversion to open surgery, early complications needing hospital monitoring or redo-operation, difficult pain management, <92 HbO2% saturation on room air or need for O2 supplementation, altered vital or laboratory parameters. Teleconsultations were scheduled as follows: the first one in afternoon of POD2, two on POD3, then once a day until chest tube removal. After discharge, patients recorded their vital signs at least four times a day using the device, which allowed two surgeons to monitor them via a mobile application. In the event of sudden changes in vital signs or the occurrence of adverse events, patients had access to a direct phone line and a dedicated re-hospitalization pathway. The primary outcome was safety, assessed by the occurrence of post-discharge complications or readmissions, as well as feasibility. Secondary outcomes: comparison of safety profile with a matched control group in which the standard of care and the evaluation of resource optimization were maintained and economic evaluation. Between July 2022 and February 2024, 48 patients were enrolled in the present study. Six patients (12.5%) dropped out due to unsatisfied discharge criteria on POD2. Exclusion causes were: significant air leaks (n:2) requiring monitoring and the use of suction device, uncontrolled pain (n:2), atrial fibrillation, and occurrence of cerebral ischemia (n:1 each). The adherence rate to vital signs monitoring by patients was 100%. A mean number of four measurements per day was performed by each patient. During telehealth home monitoring, a total of 71/2163 (1.4%) vital sign measurements violated the established acceptable threshold in 22 (52%) patients. All critical violations were managed at home. During the surveillance period (defined as the time from POD 2 to the day of chest tube removal), a persistent air leak was recorded in one patient requiring readmission to the hospital (on POD 13) and re-intervention with placement of a second thoracic drainage due to unsatisfactory lung expansion. No other postoperative complication occurred nor was there any readmission needed. Compared to the control group, the discharge gain was 2.5 days, with an economic benefit of 528 €/day (55.440 € on the total enrolled population). Our results confirm that the adoption of telehealth home monitoring is feasible and allows a safe discharge on postoperative day two after robotic surgery for stage I-II NSCLC in selected patients. A potential economic benefit (141 days of hospitalizations avoided) for the healthcare system could result from the adoption of this protocol.

摘要

尽管实施了强化康复计划,但据报道,机器人辅助肺叶切除术后的平均住院时间仍为4天。在这项前瞻性研究中,我们展示了在选定患者中,肺癌机器人辅助肺叶切除术后使用远程医疗家庭监测设备在术后第2天早期出院的结果。所有有护理人员的患者在术后第2天(POD 2),只要符合特定出院标准,即可携带远程监测设备出院。纳入标准:年龄<75岁,I-II期非小细胞肺癌,有护理人员,东部肿瘤协作组(ECOG)体能状态0-2级,计划行肺叶切除术,距离医院较近(<60公里);术后排除标准:转为开胸手术、需要住院监测或再次手术的早期并发症、疼痛管理困难、室内空气下血红蛋白氧饱和度(HbO2%)<92%或需要吸氧、生命体征或实验室参数改变。远程会诊安排如下:术后第2天下午进行第一次会诊,术后第3天进行两次会诊,然后每天一次,直至拔除胸管。出院后,患者每天至少使用该设备记录4次生命体征,两名外科医生可通过移动应用程序对其进行监测。如果生命体征突然变化或发生不良事件,患者可拨打直接电话线并使用专门的再次住院途径。主要结局是安全性,通过出院后并发症或再入院的发生情况进行评估,以及可行性。次要结局:与匹配对照组的安全性概况比较,对照组维持标准治疗和资源优化评估,以及经济评估。在2022年7月至2024年2月期间,本研究共纳入48例患者。6例患者(12.5%)因术后第2天不符合出院标准而退出。排除原因包括:需要监测和使用吸引装置的大量漏气(n=2)、疼痛控制不佳(n=2)、心房颤动以及脑缺血的发生(各n=1)。患者生命体征监测的依从率为100%。每位患者每天平均进行4次测量。在远程医疗家庭监测期间,2163次生命体征测量中有71次(1.4%)超过既定可接受阈值,涉及22例(52%)患者。所有严重违规情况均在家庭中得到处理。在监测期(定义为从术后第2天至胸管拔除日),1例患者出现持续漏气,需要再次入院(术后第13天),因肺扩张不满意再次干预并放置第二根胸腔引流管。未发生其他术后并发症,也无需再次入院。与对照组相比,出院提前了2.5天,经济效益为每天528欧元(纳入的全部患者总计55440欧元)。我们的结果证实,对于选定的I-II期非小细胞肺癌患者,采用远程医疗家庭监测在机器人辅助手术后第2天安全出院是可行的。采用该方案可能会给医疗系统带来潜在的经济效益(避免141天的住院)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3556/11508382/038906dbacea/jcm-13-06268-g001.jpg

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