Rutledge R, Croom R D, Davis J W, Berkowitz L R, Orringer E P
South Med J. 1986 Jan;79(1):28-30. doi: 10.1097/00007611-198601000-00009.
Gallstones are frequently found in patients with sickle cell anemia. The differentiation between acute calculous biliary tract disease and sickle cell crisis can be difficult and should be based on the clinical presentation, comparison with previous episodes of abdominal pain, and judicious use of hepatobiliary radionuclide scanning. Emergency cholecystectomy is associated with a high morbidity and should be avoided if possible. Elective cholecystectomy is associated with a lower but still significant risk of complications. We believe patients with sickle cell anemia and symptomatic cholelithiasis should have elective cholecystectomy. Careful management is essential to minimize the danger of postoperative complications.
镰状细胞贫血患者常并发胆结石。急性结石性胆道疾病与镰状细胞危象的鉴别可能存在困难，应依据临床表现、与既往腹痛发作情况进行比较，并谨慎运用肝胆放射性核素扫描来判断。急诊胆囊切除术的发病率较高，应尽可能避免。择期胆囊切除术的并发症风险相对较低，但仍较为显著。我们认为，患有镰状细胞贫血且有症状性胆结石的患者应接受择期胆囊切除术。细致的管理对于将术后并发症的风险降至最低至关重要。
