Doctoral School, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania.
Center of Molecular Research in Nephrology and Vascular Disease, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square No. 2, 300041 Timișoara, Romania.
Medicina (Kaunas). 2024 Oct 13;60(10):1679. doi: 10.3390/medicina60101679.
Existing tools for predicting postoperative complications in women undergoing surgery for gynecological neoplasms are evaluated in this narrative review. Although surgery is a very efficient therapy for gynecological tumors, it is not devoid of the possibility of negative postoperative outcomes. Widely used tools at present, such as the Surgical Apgar Score and the Modified Frailty Index, fail to consider the complex characteristics of gynecological malignancies and their related risk factors. A thorough search of the PubMed database was conducted for our review, specifically targeting studies that investigate several aspects impacting postoperative outcomes, including nutritional status, obesity, albumin levels, sodium levels, fluid management, and psychological well-being. Research has shown that both malnutrition and obesity have a substantial impact on postoperative mortality and morbidity. Diminished sodium and albumin levels together with compromised psychological well-being can serve as reliable indicators of negative consequences. The role of appropriate fluid management in enhancing patient recovery was also investigated. The evidence indicates that although current mechanisms are useful, they have limitations in terms of their range and do not thoroughly address these recently identified risk factors. Therefore, there is a need for a new, more comprehensive tool that combines these developing elements to more accurately forecast postoperative problems and enhance patient results in gynecological oncology. This paper highlights the need to create such a tool to improve clinical practice and the treatment of patients.
本篇叙述性综述评估了现有的预测妇科肿瘤手术患者术后并发症的工具。虽然手术是治疗妇科肿瘤的非常有效的方法,但它并非没有产生负面术后结果的可能性。目前广泛使用的工具,如手术 Apgar 评分和改良虚弱指数,都没有考虑到妇科恶性肿瘤的复杂特征及其相关的危险因素。我们对 PubMed 数据库进行了全面检索,专门针对研究术后结果的几个方面的研究,包括营养状况、肥胖、白蛋白水平、钠水平、液体管理和心理健康。研究表明,营养不良和肥胖都对术后死亡率和发病率有重大影响。低钠和白蛋白水平以及心理健康受损可以作为不良后果的可靠指标。适当的液体管理在促进患者康复方面的作用也进行了研究。有证据表明,尽管目前的机制很有用,但它们在范围上存在局限性,并且没有彻底解决这些新确定的风险因素。因此,需要一种新的、更全面的工具,将这些发展中的要素结合起来,更准确地预测术后问题,并改善妇科肿瘤学患者的治疗效果。本文强调了创建这样一种工具的必要性,以改善临床实践和患者治疗。