Suppr超能文献

带血管蒂和不带血管蒂的脂肪筋膜皮瓣在伴有肌腱损伤的组织创伤中的应用:组织学和闪烁扫描大鼠模型研究中的皮瓣存活和肌腱愈合。

Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study.

机构信息

Faculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, Turkey.

Faculty Depth of Nucleer Medicine, Pamukkale University Medicine, Denizli 20160, Turkey.

出版信息

Medicina (Kaunas). 2024 Oct 15;60(10):1689. doi: 10.3390/medicina60101689.

Abstract

: Complex wounds in the hand and distal lower extremities pose challenges in reconstructive surgery, often involving critical structures like tendons. Tendon injuries, prevalent in such wounds, necessitate optimal repair methods for functional recovery. This study investigates the impact of vascularised and nonvascularised adipofascial tissue on tendon repair, focusing on early healing stages, mobilisation, and scintigraphic evaluation of flap vascularity. Wistar Albino rats were divided into groups undergoing primary tendon repair, vascularised adipofascial flap application, or nonvascularised flap application. Scintigraphic evaluation and histopathological assessment were performed to analyse healing processes. : Pedicle-free flaps support healing in tendon injuries without negatively affecting medium-term outcomes. Vascularised flaps exhibit faster healing. The scintigraphic analysis showed that the static measurements of the late phase were statistically significantly higher in the group with the non-vascularised adipofascial flap ( = 0.038). The mean perfusion reserve was higher in the vascularised pedicled adipofascial flap group than the non-vascularised adipofascial flap group. Scintigraphic analysis highlights the viability of pedicle-free flaps. : Pedicle-free adipofascial flaps support the healing of the tendon without complicating the results, while vascularised flaps show accelerated healing. These findings provide valuable insights into optimising tendon repair strategies using adipofascial flaps, with implications for enhancing functional recovery in complex wounds.

摘要

手部和远端下肢的复杂伤口给重建手术带来了挑战,这些伤口通常涉及到肌腱等关键结构。这些伤口中常见的肌腱损伤需要采用最佳的修复方法来恢复功能。本研究旨在探讨带血管和不带血管脂肪筋膜组织对肌腱修复的影响,重点关注早期愈合阶段、活动度以及皮瓣血管化的闪烁扫描评估。将 Wistar Albino 大鼠分为三组,分别进行原发性肌腱修复、带血管脂肪筋膜皮瓣应用和不带血管皮瓣应用。采用闪烁扫描评估和组织病理学评估来分析愈合过程。研究结果表明,无蒂皮瓣支持肌腱损伤的愈合,且不会对中期结果产生负面影响。带血管的皮瓣愈合更快。闪烁扫描分析显示,无血管化脂肪筋膜皮瓣组的晚期静态测量值在统计学上显著高于非血管化脂肪筋膜皮瓣组(=0.038)。带血管蒂脂肪筋膜皮瓣组的平均灌注储备高于非血管化脂肪筋膜皮瓣组。闪烁扫描分析突出了无蒂皮瓣的活力。无蒂脂肪筋膜皮瓣支持肌腱愈合而不影响结果,而带血管皮瓣则显示出更快的愈合速度。这些发现为使用脂肪筋膜瓣优化肌腱修复策略提供了有价值的见解,对增强复杂伤口中的功能恢复具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/1c5ac3f24d0c/medicina-60-01689-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验