• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

带血管蒂和不带血管蒂的脂肪筋膜皮瓣在伴有肌腱损伤的组织创伤中的应用:组织学和闪烁扫描大鼠模型研究中的皮瓣存活和肌腱愈合。

Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study.

机构信息

Faculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, Turkey.

Faculty Depth of Nucleer Medicine, Pamukkale University Medicine, Denizli 20160, Turkey.

出版信息

Medicina (Kaunas). 2024 Oct 15;60(10):1689. doi: 10.3390/medicina60101689.

DOI:10.3390/medicina60101689
PMID:39459476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11509659/
Abstract

: Complex wounds in the hand and distal lower extremities pose challenges in reconstructive surgery, often involving critical structures like tendons. Tendon injuries, prevalent in such wounds, necessitate optimal repair methods for functional recovery. This study investigates the impact of vascularised and nonvascularised adipofascial tissue on tendon repair, focusing on early healing stages, mobilisation, and scintigraphic evaluation of flap vascularity. Wistar Albino rats were divided into groups undergoing primary tendon repair, vascularised adipofascial flap application, or nonvascularised flap application. Scintigraphic evaluation and histopathological assessment were performed to analyse healing processes. : Pedicle-free flaps support healing in tendon injuries without negatively affecting medium-term outcomes. Vascularised flaps exhibit faster healing. The scintigraphic analysis showed that the static measurements of the late phase were statistically significantly higher in the group with the non-vascularised adipofascial flap ( = 0.038). The mean perfusion reserve was higher in the vascularised pedicled adipofascial flap group than the non-vascularised adipofascial flap group. Scintigraphic analysis highlights the viability of pedicle-free flaps. : Pedicle-free adipofascial flaps support the healing of the tendon without complicating the results, while vascularised flaps show accelerated healing. These findings provide valuable insights into optimising tendon repair strategies using adipofascial flaps, with implications for enhancing functional recovery in complex wounds.

摘要

手部和远端下肢的复杂伤口给重建手术带来了挑战,这些伤口通常涉及到肌腱等关键结构。这些伤口中常见的肌腱损伤需要采用最佳的修复方法来恢复功能。本研究旨在探讨带血管和不带血管脂肪筋膜组织对肌腱修复的影响,重点关注早期愈合阶段、活动度以及皮瓣血管化的闪烁扫描评估。将 Wistar Albino 大鼠分为三组,分别进行原发性肌腱修复、带血管脂肪筋膜皮瓣应用和不带血管皮瓣应用。采用闪烁扫描评估和组织病理学评估来分析愈合过程。研究结果表明,无蒂皮瓣支持肌腱损伤的愈合,且不会对中期结果产生负面影响。带血管的皮瓣愈合更快。闪烁扫描分析显示,无血管化脂肪筋膜皮瓣组的晚期静态测量值在统计学上显著高于非血管化脂肪筋膜皮瓣组(=0.038)。带血管蒂脂肪筋膜皮瓣组的平均灌注储备高于非血管化脂肪筋膜皮瓣组。闪烁扫描分析突出了无蒂皮瓣的活力。无蒂脂肪筋膜皮瓣支持肌腱愈合而不影响结果,而带血管皮瓣则显示出更快的愈合速度。这些发现为使用脂肪筋膜瓣优化肌腱修复策略提供了有价值的见解,对增强复杂伤口中的功能恢复具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/182d71e6b174/medicina-60-01689-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/1c5ac3f24d0c/medicina-60-01689-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/54056e9ddc3f/medicina-60-01689-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/9dcf62b0118b/medicina-60-01689-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/59f4c754a6e5/medicina-60-01689-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/60349eb427c0/medicina-60-01689-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/182d71e6b174/medicina-60-01689-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/1c5ac3f24d0c/medicina-60-01689-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/54056e9ddc3f/medicina-60-01689-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/9dcf62b0118b/medicina-60-01689-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/59f4c754a6e5/medicina-60-01689-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/60349eb427c0/medicina-60-01689-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0315/11509659/182d71e6b174/medicina-60-01689-g006.jpg

相似文献

1
Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study.带血管蒂和不带血管蒂的脂肪筋膜皮瓣在伴有肌腱损伤的组织创伤中的应用:组织学和闪烁扫描大鼠模型研究中的皮瓣存活和肌腱愈合。
Medicina (Kaunas). 2024 Oct 15;60(10):1689. doi: 10.3390/medicina60101689.
2
Gliding Tissue Reconstruction Using a Dorsal Digital Adipofascial Flap in Complex Extensor Injury.应用背侧指固有动脉筋膜脂肪瓣滑行修复复杂伸肌腱损伤
Ann Plast Surg. 2020 Mar;84(3):283-287. doi: 10.1097/SAP.0000000000002047.
3
Superior Epididymal Artery-Based Paraepididymal Adipofascial Flap: An Experimental Adipofascial Flap Model in the Rat.基于附睾上动脉的附睾旁脂肪筋膜皮瓣:大鼠实验性脂肪筋膜皮瓣模型。
Ann Plast Surg. 2023 Jan 1;90(1):82-86. doi: 10.1097/SAP.0000000000003336.
4
[Wound repair and functional reconstruction of high-voltage electrical burns in wrists].[腕部高压电烧伤的创面修复与功能重建]
Zhonghua Shao Shang Za Zhi. 2017 Dec 20;33(12):738-743. doi: 10.3760/cma.j.issn.1009-2587.2017.12.004.
5
[Repair methods and clinical effects of full-thickness burn wounds deep to tendon or even bone in fingers].[手指肌腱甚至骨质深层全层烧伤创面的修复方法及临床效果]
Zhonghua Shao Shang Za Zhi. 2021 Jul 20;37(7):614-621. doi: 10.3760/cma.j.cn501120-20210114-00020.
6
Application of 3 different types of pedicled adipofascial flaps in the repair of deep dead space wounds.3种不同类型带蒂脂肪筋膜瓣在深部死腔创面修复中的应用
Wounds. 2023 Mar;35(3):47-52. doi: 10.25270/wnds/21155.
7
The reverse posterior interosseous flap and its composite flap: experience with 201 flaps.逆行骨间后动脉皮瓣及其复合组织瓣:201例皮瓣的应用经验
J Plast Reconstr Aesthet Surg. 2007;60(8):876-82. doi: 10.1016/j.bjps.2006.11.024. Epub 2007 Jan 31.
8
Do adipofascial flaps affect the mechanical properties of a repaired tendon? A biomechanical rat model study.脂肪筋膜瓣会影响修复肌腱的力学性能吗?一项大鼠生物力学模型研究。
Hand Surg Rehabil. 2019 Oct;38(5):323-327. doi: 10.1016/j.hansur.2019.07.003. Epub 2019 Aug 3.
9
Treatment of complex hand trauma using the distal ulnar and radial artery perforator-based flaps.使用基于尺动脉和桡动脉远端穿支皮瓣治疗复杂手部创伤。
Injury. 2008 Sep;39 Suppl 3:S116-24. doi: 10.1016/j.injury.2008.06.009. Epub 2008 Aug 8.
10
The cross-digital dorsal adipofascial flap.指背交叉脂肪筋膜瓣。
Ann Plast Surg. 2008 Feb;60(2):150-3. doi: 10.1097/SAP.0b013e31805a65ac.

本文引用的文献

1
An immunohistochemical and biomechanical evaluation of the effect of fat graft on tendon healing.脂肪移植对肌腱愈合影响的免疫组化和生物力学评估。
J Orthop Surg (Hong Kong). 2023 Sep-Dec;31(3):10225536231220839. doi: 10.1177/10225536231220839.
2
Comparison of the outcomes of adipofascial and two-staged fasciocutaneous reverse sural flap in patients with lower leg trauma.小腿创伤患者中脂肪筋膜瓣与两期筋膜皮逆行腓肠神经营养血管皮瓣效果的比较
J Clin Orthop Trauma. 2020 Jul 31;14:113-120. doi: 10.1016/j.jcot.2020.07.025. eCollection 2021 Mar.
3
Multi-dorsal metacarpal artery perforator adipofascial turnover flap for index to little finger reconstruction: Anatomical study and clinical application.
多背侧掌骨动脉穿支蒂 adipofascial 旋转皮瓣在示指至小指再造中的应用:解剖学研究与临床应用。
Hand Surg Rehabil. 2021 Apr;40(2):177-182. doi: 10.1016/j.hansur.2020.11.004. Epub 2020 Dec 11.
4
The medial adipofascial flap for infected tibia fractures reconstruction: 10 years of experience with 59 cases.带深筋膜蒂的内侧脂肪瓣在胫骨感染性骨折重建中的应用:59 例 10 年经验。
Ann Chir Plast Esthet. 2021 Jun;66(3):234-241. doi: 10.1016/j.anplas.2020.07.010. Epub 2020 Aug 13.
5
Distally Based Sural Adipofascial Turnover Flap for Coverage of Complicated Wound in the Foot and Ankle Region.用于覆盖足踝部复杂伤口的远端蒂腓肠脂肪筋膜翻转皮瓣
Ann Plast Surg. 2020 May;84(5):580-587. doi: 10.1097/SAP.0000000000002069.
6
Do adipofascial flaps affect the mechanical properties of a repaired tendon? A biomechanical rat model study.脂肪筋膜瓣会影响修复肌腱的力学性能吗?一项大鼠生物力学模型研究。
Hand Surg Rehabil. 2019 Oct;38(5):323-327. doi: 10.1016/j.hansur.2019.07.003. Epub 2019 Aug 3.
7
Modified single pedicle reverse adipofascial flap for fingertip reconstruction.改良单蒂逆行脂肪筋膜皮瓣在指尖再造中的应用。
Microsurgery. 2019 Mar;39(3):221-227. doi: 10.1002/micr.30404. Epub 2018 Dec 17.
8
Biomechanical evaluation of tendon regeneration with adipose-derived stem cell.脂肪来源干细胞促进肌腱再生的生物力学评估。
J Orthop Res. 2019 Jun;37(6):1281-1286. doi: 10.1002/jor.24182. Epub 2019 Jan 4.
9
The Role of the Paratenon in Achilles Tendon Healing: A Study in Rats.腱旁组织在跟腱愈合中的作用:大鼠研究。
Am J Sports Med. 2018 Apr;46(5):1214-1219. doi: 10.1177/0363546518756093. Epub 2018 Mar 5.
10
Fenestrated Adipofascial Reverse Flap: A Modified Technique for the Reconstruction of Fingertip Amputations.带孔脂肪筋膜逆行皮瓣:一种改良的指尖离断修复技术。
J Invest Surg. 2017 Dec;30(6):353-358. doi: 10.1080/08941939.2016.1251667. Epub 2016 Nov 30.